Iodine in PDB 1cmk: Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations

All present enzymatic activity of Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations:
2.7.11.11;

The structure of Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations, PDB code: 1cmk was solved by J.Zheng, D.R.Knighton, N.-H.Xuong, S.S.Taylor, J.M.Sowadski, L.F.Ten Eyck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.90
Space group	P 41 3 2
Cell size a, b, c (Å), α, β, γ (°)	171.520, 171.520, 171.520, 90.00, 90.00, 90.00
R / Rfree (%)	23.3 / n/a

The binding sites of Iodine atom in the Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations (pdb code 1cmk). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations, PDB code: 1cmk:
Jump to Iodine binding site number: 1; 2;

Iodine binding site 1 out of 2 in the Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations within 5.0Å range: probe atom residue distance (Å) B Occ I:I384 b:17.0 occ:1.00 CE2 I:TYR3 2.1 17.0 1.0 CZ I:TYR3 3.1 17.0 1.0 CD2 I:TYR3 3.1 17.0 1.0 OH I:TYR3 3.1 17.0 1.0 CG I:TYR3 4.4 17.0 1.0 CE1 I:TYR3 4.4 17.0 1.0 CG1 I:ILE7 4.7 17.0 1.0 CD1 I:TYR3 4.9 17.0 1.0

Iodine binding site 2 out of 2 in the Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Crystal Structures of the Myristylated Catalytic Subunit of Camp- Dependent Protein Kinase Reveal Open and Closed Conformations within 5.0Å range: probe atom residue distance (Å) B Occ I:I385 b:17.0 occ:1.00 CE1 I:TYR3 2.1 17.0 1.0 CD1 I:TYR3 3.0 17.0 1.0 CZ I:TYR3 3.0 17.0 1.0 OH I:TYR3 3.2 17.0 1.0 O E:GLY234 3.8 17.0 1.0 C E:GLY234 4.0 17.0 1.0 CA E:GLY234 4.0 17.0 1.0 CD2 I:PHE6 4.2 17.0 1.0 CD1 I:ILE7 4.3 17.0 1.0 O E:GLY136 4.3 17.0 1.0 CG I:TYR3 4.3 17.0 1.0 CE2 I:PHE6 4.3 17.0 1.0 CE2 I:TYR3 4.4 17.0 1.0 N E:TYR235 4.8 17.0 1.0 CD2 I:TYR3 4.8 17.0 1.0 CA E:GLY136 4.8 17.0 1.0 CD2 E:TYR235 4.9 17.0 1.0 C E:GLY136 4.9 17.0 1.0

J.Zheng, D.R.Knighton, N.H.Xuong, S.S.Taylor, J.M.Sowadski, L.F.Ten Eyck. Crystal Structures of the Myristylated Catalytic Subunit of Camp-Dependent Protein Kinase Reveal Open and Closed Conformations. Protein Sci. V. 2 1559 1993.
ISSN: ISSN 0961-8368
PubMed: 8251932