Atomistry » Iodine » PDB 1a31-1ga5 » 1ecv
Atomistry »
  Iodine »
    PDB 1a31-1ga5 »
      1ecv »

Iodine in PDB 1ecv: Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid

Enzymatic activity of Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid

All present enzymatic activity of Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid:
3.1.3.48;

Protein crystallography data

The structure of Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid, PDB code: 1ecv was solved by H.S.Andersen, L.F.Iversen, S.Branner, H.B.Rasmussen, N.P.H.Moller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 6.00 / 1.95
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 87.870, 87.870, 103.120, 90.00, 90.00, 120.00
R / Rfree (%) 19.4 / 24.9

Iodine Binding Sites:

The binding sites of Iodine atom in the Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid (pdb code 1ecv). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid, PDB code: 1ecv:

Iodine binding site 1 out of 1 in 1ecv

Go back to Iodine Binding Sites List in 1ecv
Iodine binding site 1 out of 1 in the Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed with 5- Iodo-2-(Oxalyl-Amino)-Benzoic Acid within 5.0Å range:
probe atom residue distance (Å) B Occ
A:I301

b:26.5
occ:1.00
 I19 A:878301 0.0 26.5 1.0
C6 A:878301 2.1 14.7 1.0
C5 A:878301 3.0 11.4 1.0
C1 A:878301 3.1 10.5 1.0
CG1 A:VAL49 4.0 14.3 1.0
CB A:TYR46 4.1 9.9 1.0
CD1 A:TYR46 4.1 11.8 1.0
CG A:TYR46 4.1 11.5 1.0
CH3 A:ACT302 4.2 22.1 1.0
C4 A:878301 4.3 12.0 1.0
C2 A:878301 4.4 7.4 1.0
O A:HOH364 4.5 29.7 1.0
CB A:ASP48 4.6 13.4 1.0
C3 A:878301 4.9 7.8 1.0
CE1 A:TYR46 4.9 12.6 1.0
CD2 A:TYR46 4.9 10.7 1.0

Reference:

H.S.Andersen, L.F.Iversen, C.B.Jeppesen, S.Branner, K.Norris, H.B.Rasmussen, K.B.Moller, N.P.Moller. 2-(Oxalylamino)-Benzoic Acid Is A General, Competitive Inhibitor of Protein-Tyrosine Phosphatases. J.Biol.Chem. V. 275 7101 2000.
ISSN: ISSN 0021-9258
PubMed: 10702277
DOI: 10.1074/JBC.275.10.7101
Page generated: Sun Dec 13 19:19:19 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy