Iodine in PDB 1lei: The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription

The structure of The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription, PDB code: 1lei was solved by F.Chen-Park, D.B.Huang, G.Ghosh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.70
Space group	C 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	137.131, 179.697, 97.068, 90.00, 90.00, 90.00
R / Rfree (%)	25 / 28.4

The binding sites of Iodine atom in the The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription (pdb code 1lei). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 4 binding sites of Iodine where determined in the The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription, PDB code: 1lei:
Jump to Iodine binding site number: 1; 2; 3; 4;

Iodine binding site 1 out of 4 in the The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription within 5.0Å range: probe atom residue distance (Å) B Occ D:I5 b:52.8 occ:1.00 I5 D:5IU5 0.0 52.8 1.0 C5 D:5IU5 1.6 53.2 1.0 C6 D:5IU5 2.6 51.7 1.0 C4 D:5IU5 2.7 53.3 1.0 O4 D:5IU5 3.1 54.6 1.0 N7 D:DG4 3.8 49.3 1.0 NH1 A:ARG33 3.8 27.7 1.0 C8 D:DG4 3.8 48.7 1.0 CZ A:ARG33 3.9 27.8 1.0 NE A:ARG33 3.9 26.9 1.0 CD A:ARG33 3.9 26.9 1.0 N3 D:5IU5 3.9 52.5 1.0 N1 D:5IU5 3.9 50.3 1.0 O A:HOH707 4.2 25.4 1.0 C5 D:DG4 4.3 49.9 1.0 N9 D:DG4 4.4 49.1 1.0 C2 D:5IU5 4.5 51.3 1.0 NH2 A:ARG33 4.5 28.7 1.0 C4 D:DG4 4.6 49.9 1.0 C2' D:DG4 4.9 47.6 1.0

Iodine binding site 2 out of 4 in the The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription within 5.0Å range: probe atom residue distance (Å) B Occ D:I8 b:81.7 occ:1.00 I5 D:5IU8 0.0 81.7 1.0 C5 D:5IU8 1.7 78.7 1.0 C6 D:5IU8 2.6 77.3 1.0 C4 D:5IU8 2.7 78.1 1.0 O4 D:5IU8 3.1 78.0 1.0 C6 D:DC7 3.8 60.8 1.0 C5 D:DC7 3.8 60.0 1.0 N3 D:5IU8 3.9 77.0 1.0 N1 D:5IU8 3.9 75.9 1.0 N1 D:DC7 4.2 61.3 1.0 C4 D:DC7 4.3 60.3 1.0 I5 D:5IU9 4.5 81.9 1.0 OP2 D:5IU8 4.5 64.8 1.0 C2 D:5IU8 4.5 76.5 1.0 O4 D:5IU9 4.6 79.8 1.0 C3' D:DC7 4.6 61.3 1.0 C2 D:DC7 4.7 61.3 1.0 N3 D:DC7 4.7 60.7 1.0 C2' D:DC7 4.7 61.7 1.0 O5' D:DC7 4.9 56.8 1.0 OP2 D:DC7 4.9 54.8 1.0 C4 D:5IU9 5.0 79.1 1.0 N4 D:DC7 5.0 60.6 1.0 C5 D:5IU9 5.0 79.5 1.0 C1' D:DC7 5.0 61.3 1.0

Iodine binding site 3 out of 4 in the The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 3 of The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription within 5.0Å range: probe atom residue distance (Å) B Occ D:I9 b:81.9 occ:1.00 I5 D:5IU9 0.0 81.9 1.0 C5 D:5IU9 1.7 79.5 1.0 C6 D:5IU9 2.6 78.2 1.0 C4 D:5IU9 2.7 79.1 1.0 O4 D:5IU9 3.0 79.8 1.0 NZ B:LYS241 3.3 62.9 1.0 CE B:LYS241 3.5 64.5 1.0 CD B:LYS241 3.7 64.8 1.0 N3 D:5IU9 3.9 77.9 1.0 N1 D:5IU9 3.9 76.8 1.0 C6 D:5IU8 4.0 77.3 1.0 C5 D:5IU8 4.1 78.7 1.0 OH B:TYR57 4.1 55.8 1.0 N1 D:5IU8 4.4 75.9 1.0 I5 D:5IU8 4.5 81.7 1.0 CE2 B:TYR57 4.5 56.7 1.0 C2 D:5IU9 4.5 77.1 1.0 CG B:LYS241 4.5 64.7 1.0 C4 D:5IU8 4.6 78.1 1.0 CZ B:TYR57 4.7 56.6 1.0 C2' D:5IU8 4.7 73.0 1.0 C2 D:5IU8 4.8 76.5 1.0 N3 D:5IU8 4.9 77.0 1.0 I5 D:5IU10 4.9 66.6 1.0

Iodine binding site 4 out of 4 in the The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 4 of The Kb Dna Sequence From the Hlv-Ltr Functions As An Allosteric Regulator of Hiv Transcription within 5.0Å range: probe atom residue distance (Å) B Occ D:I10 b:66.6 occ:1.00 I5 D:5IU10 0.0 66.6 1.0 C5 D:5IU10 1.6 69.9 1.0 C6 D:5IU10 2.6 69.9 1.0 C4 D:5IU10 2.7 69.7 1.0 O4 D:5IU10 3.0 70.0 1.0 NZ B:LYS241 3.1 62.9 1.0 OE1 B:GLU60 3.2 68.9 1.0 CD B:GLU60 3.3 70.1 1.0 OE2 B:GLU60 3.4 70.0 1.0 CD2 B:TYR57 3.6 57.6 1.0 N1 D:5IU9 3.8 76.8 1.0 C6 D:5IU9 3.8 78.2 1.0 CG B:TYR57 3.9 58.5 1.0 N1 D:5IU10 3.9 70.6 1.0 N3 D:5IU10 3.9 69.5 1.0 C2 D:5IU9 3.9 77.1 1.0 CE2 B:TYR57 3.9 56.7 1.0 C2' D:5IU9 4.0 74.5 1.0 CG B:GLU60 4.0 71.0 1.0 C5 D:5IU9 4.0 79.5 1.0 N3 D:5IU9 4.1 77.9 1.0 C4 D:5IU9 4.2 79.1 1.0 CB B:TYR57 4.2 60.3 1.0 C1' D:5IU9 4.4 75.7 1.0 C2 D:5IU10 4.4 69.7 1.0 O2 D:5IU9 4.5 76.8 1.0 CD1 B:TYR57 4.5 57.5 1.0 SG B:CYS59 4.5 67.5 1.0 CZ B:TYR57 4.6 56.6 1.0 CE B:LYS241 4.6 64.5 1.0 CE1 B:TYR57 4.8 56.4 1.0 C3' D:5IU9 4.9 73.6 1.0 O4' D:5IU10 4.9 73.4 1.0 I5 D:5IU9 4.9 81.9 1.0 O4 D:5IU9 4.9 79.8 1.0 C5 D:DC11 5.0 84.3 1.0 N4 D:DC11 5.0 84.4 1.0

F.E.Chen-Park, D.B.Huang, B.Noro, D.Thanos, G.Ghosh. The Kb Dna Sequence From the Hiv Long Terminal Repeat Functions As An Allosteric Regulator of Hiv Transcription J.Biol.Chem. V. 277 24701 2002.
ISSN: ISSN 0021-9258
PubMed: 11970949
DOI: 10.1074/JBC.M200007200