Iodine in PDB 1oj5: Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif

The structure of Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif, PDB code: 1oj5 was solved by A.Razeto, V.Ramakrishnan, K.Giller, N.Lakomek, T.Carlomagno, C.Griesinger, M.Lodrini, C.M.Litterst, E.Pftizner, S.Becker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.21 / 2.2
Space group	P 62
Cell size a, b, c (Å), α, β, γ (°)	62.100, 62.100, 73.400, 90.00, 90.00, 120.00
R / Rfree (%)	16.6 / 21.4

The binding sites of Iodine atom in the Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif (pdb code 1oj5). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 5 binding sites of Iodine where determined in the Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif, PDB code: 1oj5:
Jump to Iodine binding site number: 1; 2; 3; 4; 5;

Iodine binding site 1 out of 5 in the Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:I1368 b:31.7 occ:0.70 OG A:SER274 3.5 36.6 1.0 CB A:ASP276 3.9 35.3 1.0 N A:ASP276 4.0 34.4 1.0 O A:SER274 4.0 32.9 1.0 C A:SER274 4.1 34.3 1.0 N A:LYS265 4.1 33.7 1.0 CB A:SER274 4.1 35.3 1.0 C A:ILE275 4.1 34.4 1.0 C A:THR264 4.2 33.6 1.0 CE A:MET263 4.2 39.4 0.4 O A:MET263 4.2 32.6 1.0 N A:ILE275 4.3 34.1 1.0 CB A:MET263 4.3 34.9 1.0 CB A:LYS265 4.3 34.2 1.0 CA A:ILE275 4.3 34.3 1.0 C A:MET263 4.4 33.3 1.0 CA A:THR264 4.4 33.0 1.0 CE A:MET359 4.4 33.1 0.5 CA A:ASP276 4.5 34.9 1.0 N A:THR264 4.6 33.5 1.0 O A:THR264 4.6 33.8 1.0 O A:ILE275 4.7 35.2 1.0 CA A:SER274 4.8 34.8 1.0 CA A:LYS265 4.8 34.1 1.0 O A:HOH2020 4.9 63.2 1.0

Iodine binding site 2 out of 5 in the Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:I1369 b:36.0 occ:0.40 O A:HOH2055 3.7 48.1 1.0 CG A:GLN315 3.7 38.7 1.0 CG A:PRO307 4.0 38.6 1.0 CA A:GLN312 4.1 32.1 1.0 CG A:GLN312 4.2 32.2 1.0 CB A:GLN315 4.2 35.6 1.0 CB A:PRO307 4.3 38.7 1.0 O A:ARG311 4.4 31.4 1.0 CG A:ARG311 4.5 34.5 1.0 N A:GLN312 4.5 32.0 1.0 C A:ARG311 4.6 31.8 1.0 CB A:GLN312 4.6 32.3 1.0 CD A:PRO307 5.0 39.6 1.0

Iodine binding site 3 out of 5 in the Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 3 of Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:I1370 b:36.3 occ:0.20 O A:HOH2010 2.9 34.9 1.0 O A:HOH2009 3.0 35.0 0.5 OD1 A:ASP276 3.4 37.9 1.0 OG A:SER278 3.4 36.8 0.5 O A:ASP276 3.4 34.1 1.0 N A:SER279 3.6 38.3 1.0 SD A:MET263 3.7 39.1 0.4 CB A:SER279 3.7 39.1 1.0 CG A:ASP276 3.7 37.4 1.0 N A:SER278 4.1 36.1 1.0 C A:ASP276 4.1 34.4 1.0 CG A:MET263 4.1 37.3 0.6 CG A:MET263 4.2 36.2 0.4 CB A:ASP276 4.2 35.3 1.0 CA A:SER279 4.2 38.8 1.0 OD2 A:ASP276 4.3 43.1 1.0 CB A:SER278 4.4 36.5 0.5 N A:MET263 4.4 33.1 1.0 CA A:PHE262 4.4 32.9 1.0 CB A:SER278 4.5 36.5 0.5 C A:SER278 4.5 37.5 1.0 CA A:SER278 4.5 36.7 1.0 O A:SER261 4.5 35.3 1.0 C A:THR277 4.7 35.3 1.0 N A:THR277 4.7 34.3 1.0 C A:PHE262 4.8 33.2 1.0 CB A:MET263 4.8 34.9 1.0 CE A:MET263 4.8 39.4 0.4 CA A:ASP276 4.8 34.9 1.0 OG A:SER279 4.8 42.4 1.0 CA A:THR277 4.9 34.8 1.0 O A:HOH2022 5.0 52.9 1.0

Iodine binding site 4 out of 5 in the Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 4 of Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:I1371 b:32.4 occ:0.50 O A:HOH2049 1.2 19.8 0.5 N A:SER308 3.6 33.9 1.0 O A:HOH2050 4.0 38.6 1.0 CA A:PRO307 4.0 37.9 1.0 O A:HOH2097 4.0 42.3 1.0 OG A:SER308 4.1 30.3 1.0 CB A:SER308 4.3 31.8 1.0 C A:PRO307 4.3 36.1 1.0 CB A:PRO307 4.4 38.7 1.0 CG A:PRO302 4.4 40.8 1.0 CB A:ARG311 4.6 32.0 1.0 CA A:SER308 4.6 32.4 1.0 CA A:PRO302 4.7 40.9 1.0 CB A:PRO302 4.7 41.0 1.0 O A:HOH2005 4.9 77.5 1.0 CG A:ARG311 4.9 34.5 1.0 CD A:PRO302 5.0 39.9 1.0

Iodine binding site 5 out of 5 in the Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 5 of Crystal Structure of the Nco-A1 Pas-B Domain Bound to the STAT6 Transactivation Domain Lxxll Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:I1372 b:31.1 occ:0.20 O A:HOH2026 1.2 34.6 0.5 O A:HOH2087 3.1 40.1 1.0 O B:LEU806 4.0 47.3 1.0 O B:HOH2018 4.3 90.8 1.0 NH1 A:ARG281 4.3 50.0 1.0 O B:LEU807 4.6 52.7 1.0 CZ A:ARG281 4.6 48.7 1.0 NE A:ARG281 4.8 47.5 1.0 O A:HOH2024 4.8 43.7 1.0 CD A:ARG281 4.9 42.9 1.0

A.Razeto, V.Ramakrishnan, C.M.Litterst, K.Giller, C.Griesinger, T.Carlomagno, N.Lakomek, T.Heimburg, M.Lodrini, E.Pfitzner, S.Becker. Structure of the Ncoa-1/Src-1 Pas-B Domain Bound to the Lxxll Motif of the STAT6 Transactivation Domain J.Mol.Biol. V. 336 319 2004.
ISSN: ISSN 0022-2836
PubMed: 14757047
DOI: 10.1016/J.JMB.2003.12.057