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Atomistry » Iodine » PDB 1lkr-1pvh » 1pge | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iodine » PDB 1lkr-1pvh » 1pge » |
Iodine in PDB 1pge: Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen)Enzymatic activity of Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen)
All present enzymatic activity of Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen):
1.14.99.1; Protein crystallography data
The structure of Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen), PDB code: 1pge
was solved by
P.J.Loll,
D.Picot,
R.M.Garavito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1pge:
The structure of Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen) also contains other interesting chemical elements:
Iodine Binding Sites:
The binding sites of Iodine atom in the Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen)
(pdb code 1pge). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen), PDB code: 1pge: Jump to Iodine binding site number: 1; 2; Iodine binding site 1 out of 2 in 1pgeGo back to Iodine Binding Sites List in 1pge
Iodine binding site 1 out
of 2 in the Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen)
Mono view Stereo pair view
Iodine binding site 2 out of 2 in 1pgeGo back to Iodine Binding Sites List in 1pge
Iodine binding site 2 out
of 2 in the Prostaglandin H2 Synthase-1 Complexed with P-(2'-Iodo-5'-Thenoyl) Hydrotropic Acid (Iodosuprofen)
Mono view Stereo pair view
Reference:
P.J.Loll,
D.Picot,
O.Ekabo,
R.M.Garavito.
Synthesis and Use of Iodinated Nonsteroidal Antiinflammatory Drug Analogs As Crystallographic Probes of the Prostaglandin H2 Synthase Cyclooxygenase Active Site. Biochemistry V. 35 7330 1996.
Page generated: Sun Aug 11 12:35:24 2024
ISSN: ISSN 0006-2960 PubMed: 8652509 DOI: 10.1021/BI952776W |
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