Iodine in PDB 1pvh: Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130

The structure of Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130, PDB code: 1pvh was solved by M.J.Boulanger, A.J.Bankovich, T.Kortemme, D.Baker, K.C.Garcia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.86 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	79.710, 86.700, 146.430, 90.00, 90.00, 90.00
R / Rfree (%)	24.8 / 28.9

The binding sites of Iodine atom in the Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130 (pdb code 1pvh). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130, PDB code: 1pvh:
Jump to Iodine binding site number: 1; 2;

Iodine binding site 1 out of 2 in the Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130 within 5.0Å range: probe atom residue distance (Å) B Occ A:I302 b:44.1 occ:1.00 O A:HOH338 3.5 48.8 1.0 N A:TRP288 3.7 33.8 1.0 CA A:TYR287 4.1 34.8 1.0 CD1 A:TRP288 4.2 34.0 1.0 CB A:TYR287 4.3 33.1 1.0 C A:TYR287 4.4 35.3 1.0 CB A:TRP288 4.4 32.1 1.0 CD2 A:TYR287 4.4 32.1 1.0 CA A:TRP288 4.6 34.1 1.0 CG A:TRP288 4.7 34.4 1.0 CG A:TYR287 4.9 30.6 1.0 O A:GLY286 5.0 38.3 1.0

Iodine binding site 2 out of 2 in the Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Crystal Structure of Leukemia Inhibitory Factor in Complex with GP130 within 5.0Å range: probe atom residue distance (Å) B Occ D:I202 b:43.8 occ:1.00 N D:GLY140 3.7 57.9 1.0 CA D:HIS138 3.7 53.3 1.0 C D:HIS138 3.8 52.7 1.0 O D:HIS138 3.9 52.2 1.0 CA D:GLY140 4.0 59.9 1.0 CB D:HIS138 4.0 54.4 1.0 SG D:CYS12 4.2 52.4 1.0 N D:VAL139 4.4 53.8 1.0 C D:VAL139 4.8 56.3 1.0 O D:CYS134 4.8 49.3 1.0 CB D:CYS12 4.9 50.4 1.0 C D:GLY140 5.0 61.5 1.0 CG D:HIS138 5.0 55.5 1.0

M.J.Boulanger, A.J.Bankovich, T.Kortemme, D.Baker, K.C.Garcia. Convergent Mechanisms For Recognition of Divergent Cytokines By the Shared Signaling Receptor GP130. Mol.Cell V. 12 577 2003.
ISSN: ISSN 1097-2765
PubMed: 14527405
DOI: 10.1016/S1097-2765(03)00365-4