Iodine in PDB 1s6r: 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid

All present enzymatic activity of 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid:
3.5.2.6;

The structure of 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid, PDB code: 1s6r was solved by J.Wouters, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.24
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	46.381, 83.763, 95.810, 90.00, 90.00, 90.00
R / Rfree (%)	22.6 / 29.3

The binding sites of Iodine atom in the 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid (pdb code 1s6r). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid, PDB code: 1s6r:

Iodine binding site 1 out of 1 in the 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:I1 b:0.2 occ:1.00 I A:IAP1 0.0 0.2 1.0 C8 A:IAP1 2.1 44.9 1.0 C7 A:IAP1 3.0 44.5 1.0 N1 A:IAP1 3.1 42.9 1.0 O3 A:IAP1 4.1 46.7 1.0 N A:GLY320 4.1 24.3 1.0 C5 A:IAP1 4.3 40.9 1.0 CA A:THR319 4.4 23.9 1.0 C A:THR319 4.6 24.0 1.0 CB A:THR319 4.8 23.7 1.0 CA A:GLY320 4.9 24.5 1.0 C6 A:IAP1 5.0 39.3 1.0 CE1 A:TYR221 5.0 31.9 1.0

J.Wouters, E.Fonze, M.Vermeire, J.M.Frere, P.Charlier. Crystal Structure of Enterobacter Cloacae 908R Class C Beta-Lactamase Bound to Iodo-Acetamido-Phenyl Boronic Acid, A Transition-State Analogue. Cell.Mol.Life Sci. V. 60 1764 2003.
ISSN: ISSN 1420-682X
PubMed: 14521155
DOI: 10.1007/S00018-003-3189-2