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Atomistry » Iodine » PDB 1q0t-1v1f » 1so2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iodine » PDB 1q0t-1v1f » 1so2 » |
Iodine in PDB 1so2: Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine InhibitorEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor, PDB code: 1so2
was solved by
G.Scapin,
S.B.Patel,
C.Chung,
J.P.Varnerin,
S.D.Edmondson,
A.Mastracchio,
E.R.Parmee,
J.W.Becker,
S.B.Singh,
L.H.Van Derploeg,
M.R.Tota,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1so2:
The structure of Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor also contains other interesting chemical elements:
Iodine Binding Sites:
The binding sites of Iodine atom in the Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor
(pdb code 1so2). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total 4 binding sites of Iodine where determined in the Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor, PDB code: 1so2: Jump to Iodine binding site number: 1; 2; 3; 4; Iodine binding site 1 out of 4 in 1so2Go back to Iodine Binding Sites List in 1so2
Iodine binding site 1 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor
Mono view Stereo pair view
Iodine binding site 2 out of 4 in 1so2Go back to Iodine Binding Sites List in 1so2
Iodine binding site 2 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor
Mono view Stereo pair view
Iodine binding site 3 out of 4 in 1so2Go back to Iodine Binding Sites List in 1so2
Iodine binding site 3 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor
Mono view Stereo pair view
Iodine binding site 4 out of 4 in 1so2Go back to Iodine Binding Sites List in 1so2
Iodine binding site 4 out
of 4 in the Catalytic Domain of Human Phosphodiesterase 3B in Complex with A Dihydropyridazine Inhibitor
Mono view Stereo pair view
Reference:
G.Scapin,
S.B.Patel,
C.Chung,
J.P.Varnerin,
S.D.Edmondson,
A.Mastracchio,
E.R.Parmee,
S.B.Singh,
J.W.Becker,
L.H.Van Der Ploeg,
M.R.Tota.
Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis For Substrate and Inhibitor Specificity Biochemistry V. 43 6091 2004.
Page generated: Sun Aug 11 12:48:24 2024
ISSN: ISSN 0006-2960 PubMed: 15147193 DOI: 10.1021/BI049868I |
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