Iodine in PDB 2g1m: Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)

The structure of Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2), PDB code: 2g1m was solved by M.A.Mcdonough, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.71 / 2.20
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	110.742, 110.742, 39.986, 90.00, 90.00, 120.00
R / Rfree (%)	21.6 / 28.9

The structure of Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Iodine atom in the Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) (pdb code 2g1m). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2), PDB code: 2g1m:

Iodine binding site 1 out of 1 in the Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) within 5.0Å range: probe atom residue distance (Å) B Occ A:I701 b:57.3 occ:1.00 I1 A:4HG701 0.0 57.3 1.0 C3 A:4HG701 2.1 27.2 1.0 O A:HOH1088 2.6 15.0 1.0 C2 A:4HG701 3.0 27.5 1.0 C6 A:4HG701 3.0 15.6 1.0 C7 A:4HG701 3.2 18.1 1.0 O A:HOH1089 3.3 43.5 1.0 O A:HOH1077 3.6 49.1 1.0 OH A:TYR310 3.7 33.6 1.0 O A:HOH1036 3.9 29.2 1.0 O A:HOH1027 4.1 28.2 1.0 C1 A:4HG701 4.3 22.8 1.0 C5 A:4HG701 4.4 17.3 1.0 N1 A:4HG701 4.5 16.5 1.0 CZ A:TYR310 4.7 33.1 1.0 C4 A:4HG701 4.9 21.8 1.0 CH2 A:TRP389 4.9 19.2 1.0

M.A.Mcdonough, V.Li, E.Flashman, R.Chowdhury, C.Mohr, B.M.Lienard, J.Zondlo, N.J.Oldham, I.J.Clifton, J.Lewis, L.A.Mcneill, R.J.Kurzeja, K.S.Hewitson, E.Yang, S.Jordan, R.S.Syed, C.J.Schofield. Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2). Proc.Natl.Acad.Sci.Usa V. 103 9814 2006.
ISSN: ISSN 0027-8424
PubMed: 16782814
DOI: 10.1073/PNAS.0601283103