Iodine in PDB 2hq6: Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens

The structure of Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens, PDB code: 2hq6 was solved by J.R.Walker, T.Davis, R.Paramanathan, E.M.Newman, P.J.Finerty Jr., F.Mackenzie, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, S.Dhe-Paganon, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.70 / 1.75
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	84.433, 84.433, 55.289, 90.00, 90.00, 120.00
R / Rfree (%)	16.7 / 18.1

The binding sites of Iodine atom in the Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens (pdb code 2hq6). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens, PDB code: 2hq6:
Jump to Iodine binding site number: 1; 2;

Iodine binding site 1 out of 2 in the Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ A:I174 b:48.2 occ:1.00 CG2 A:THR20 3.7 30.8 1.0 CB A:LYS162 3.8 34.9 1.0 O A:HOH308 3.8 56.8 1.0 CG A:LYS162 4.1 39.1 1.0 CA A:LYS162 4.3 30.7 1.0 CD A:LYS160 4.5 46.8 1.0 CD A:LYS162 4.7 46.1 1.0 N A:LYS162 4.7 28.6 1.0 CB A:LYS160 4.8 32.6 1.0

Iodine binding site 2 out of 2 in the Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Structure of the CYCLOPHILIN_CECYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ A:I175 b:42.9 occ:1.00 CD1 A:TYR139 4.0 36.0 1.0 NH2 A:ARG96 4.0 33.8 1.0 CB A:TYR139 4.2 31.6 1.0 CD1 A:LEU142 4.2 33.6 1.0 CA A:TYR139 4.2 29.9 1.0 N A:TYR139 4.6 30.1 1.0 CG A:TYR139 4.6 32.1 1.0 CG1 A:VAL138 4.9 34.2 1.0 O A:HOH193 4.9 31.3 1.0

T.L.Davis, J.R.Walker, V.Campagna-Slater, P.J.Finerty, R.Paramanathan, G.Bernstein, F.Mackenzie, W.Tempel, H.Ouyang, W.H.Lee, E.Z.Eisenmesser, S.Dhe-Paganon. Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases. Plos Biol. V. 8 00439 2010.
ISSN: ESSN 1545-7885
PubMed: 20676357
DOI: 10.1371/JOURNAL.PBIO.1000439