Iodine in PDB 2pfi: Crystal Structure of the Cytoplasmic Domain of the Human Chloride Channel Clc-Ka

The structure of Crystal Structure of the Cytoplasmic Domain of the Human Chloride Channel Clc-Ka, PDB code: 2pfi was solved by S.Markovic, R.Dutzler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.89 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	35.283, 83.421, 59.888, 90.00, 92.48, 90.00
R / Rfree (%)	20 / 21.8

The structure of Crystal Structure of the Cytoplasmic Domain of the Human Chloride Channel Clc-Ka also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Iodine atom in the Crystal Structure of the Cytoplasmic Domain of the Human Chloride Channel Clc-Ka (pdb code 2pfi). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Crystal Structure of the Cytoplasmic Domain of the Human Chloride Channel Clc-Ka, PDB code: 2pfi:

Iodine binding site 1 out of 1 in the Crystal Structure of the Cytoplasmic Domain of the Human Chloride Channel Clc-Ka


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structure of the Cytoplasmic Domain of the Human Chloride Channel Clc-Ka within 5.0Å range: probe atom residue distance (Å) B Occ A:I501 b:31.0 occ:1.00 O A:HOH156 3.6 32.6 1.0 CD A:ARG596 3.8 26.5 1.0 NE A:ARG596 4.0 24.9 1.0 CG A:ARG596 4.0 20.0 1.0 CA A:ALA597 4.0 24.9 1.0 N A:ALA597 4.2 21.4 1.0 CG2 A:VAL600 4.3 26.6 1.0 CB A:ALA597 4.4 27.5 1.0 C A:ARG596 4.5 20.8 1.0 CB A:ARG596 4.6 21.5 1.0 O A:ARG596 4.7 23.5 1.0 O A:HOH99 4.9 36.2 1.0 CB A:VAL600 4.9 26.7 1.0

S.Markovic, R.Dutzler. The Structure of the Cytoplasmic Domain of the Chloride Channel Clc-Ka Reveals A Conserved Interaction Interface. Structure V. 15 715 2007.
ISSN: ISSN 0969-2126
PubMed: 17562318
DOI: 10.1016/J.STR.2007.04.013