Iodine in PDB 2vgz: Crystal Structure of Human Kynurenine Aminotransferase II

All present enzymatic activity of Crystal Structure of Human Kynurenine Aminotransferase II:
2.6.1.39; 2.6.1.7;

The structure of Crystal Structure of Human Kynurenine Aminotransferase II, PDB code: 2vgz was solved by F.Rossi, S.Garavaglia, V.Montalbano, M.A.Walsh, M.Rizzi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.59 / 2.3
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	99.631, 154.956, 61.201, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 24.3

The binding sites of Iodine atom in the Crystal Structure of Human Kynurenine Aminotransferase II (pdb code 2vgz). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Crystal Structure of Human Kynurenine Aminotransferase II, PDB code: 2vgz:

Iodine binding site 1 out of 1 in the Crystal Structure of Human Kynurenine Aminotransferase II


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structure of Human Kynurenine Aminotransferase II within 5.0Å range: probe atom residue distance (Å) B Occ A:I1426 b:45.1 occ:1.00 NZ A:LYS123 3.5 33.9 1.0 NZ B:LYS123 3.5 39.6 1.0 NE2 A:GLN119 3.6 30.4 1.0 NE2 B:GLN119 3.6 36.1 1.0 CE A:LYS123 3.8 34.0 1.0 O A:HOH2079 3.8 37.6 1.0 CE B:LYS123 3.9 40.8 1.0 CG2 B:THR292 4.0 28.7 1.0 OG A:SER291 4.0 31.1 1.0 OG B:SER291 4.0 32.2 1.0 CG A:GLN119 4.0 31.5 1.0 CB B:SER291 4.1 30.8 1.0 O B:HOH2079 4.2 47.6 1.0 CG B:GLN119 4.2 33.9 1.0 CB A:SER291 4.2 29.9 1.0 CG2 A:THR292 4.2 28.7 1.0 CD A:GLN119 4.3 31.5 1.0 CD B:GLN119 4.4 36.0 1.0

F.Rossi, S.Garavaglia, V.Montalbano, M.A.Walsh, M.Rizzi. Crystal Structure of Human Kynurenine Aminotransferase II, A Drug Target For the Treatment of Schizophrenia. J.Biol.Chem. V. 283 3559 2008.
ISSN: ISSN 0021-9258
PubMed: 18056996
DOI: 10.1074/JBC.M707925200