Iodine in PDB 3skq: MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane

The structure of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane, PDB code: 3skq was solved by D.Lupo, I.Tews, I.Sinning, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.10
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	124.527, 52.033, 47.232, 90.00, 108.65, 90.00
R / Rfree (%)	19.5 / 22.7

The structure of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane also contains other interesting chemical elements:

Potassium

(K)

1 atom

The binding sites of Iodine atom in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane (pdb code 3skq). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 8 binding sites of Iodine where determined in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane, PDB code: 3skq:
Jump to Iodine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Iodine binding site 1 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I1 b:48.6 occ:1.00 O A:HOH136 3.1 48.3 1.0 O A:HOH54 3.4 43.6 1.0 N A:GLU210 3.7 54.2 1.0 CB A:GLU210 3.9 61.9 1.0 CG A:MET247 4.0 24.0 1.0 CB A:MET247 4.2 20.6 1.0 CD A:LYS214 4.2 41.2 1.0 OE1 A:GLU210 4.2 67.8 1.0 CE A:LYS249 4.2 40.7 1.0 CA A:MET247 4.3 21.4 1.0 NZ A:LYS249 4.3 43.6 1.0 CG2 A:ILE209 4.4 45.4 1.0 CG A:GLU210 4.4 64.5 1.0 CA A:GLU210 4.4 57.5 1.0 CA A:ILE209 4.5 50.9 1.0 NZ A:LYS214 4.5 47.9 1.0 CD A:GLU210 4.5 68.5 1.0 C A:ILE209 4.6 54.8 1.0 CB A:ILE209 4.8 43.1 1.0 O A:MET247 4.9 25.9 1.0 SD A:MET247 4.9 30.7 1.0 CG1 A:ILE209 4.9 35.1 1.0

Iodine binding site 2 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I2 b:48.3 occ:1.00 O A:HOH53 2.8 33.2 1.0 O A:HOH60 3.2 45.9 1.0 O A:HOH39 3.4 35.5 1.0 ND2 A:ASN250 3.6 18.4 1.0 CG A:ARG285 3.8 30.2 1.0 CB A:ASN250 4.0 17.4 1.0 CG A:ASN250 4.3 18.2 1.0 CD1 A:LEU288 4.4 23.3 1.0 CD A:ARG285 4.4 35.8 1.0 CB A:ARG285 4.4 26.5 1.0 NE A:ARG285 4.5 39.8 1.0 CA A:ARG285 4.6 25.2 1.0 CB A:LEU288 4.9 18.6 1.0 CD1 A:LEU254 4.9 17.2 1.0 OD1 A:ASP251 5.0 42.9 1.0

Iodine binding site 3 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 3 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I3 b:28.1 occ:0.60 OG A:SER258 3.2 23.3 1.0 CB A:PRO260 3.9 24.6 1.0 CG2 A:THR197 3.9 18.9 1.0 CG A:PRO260 4.1 26.3 1.0 CB A:SER258 4.2 25.4 1.0 CG A:GLN261 4.4 20.4 1.0 CZ A:PHE193 4.4 29.5 1.0 CB A:THR197 4.4 21.9 1.0 CD A:PRO260 4.5 23.6 1.0 N A:GLN261 4.7 21.9 1.0 CD A:GLN261 4.7 20.4 1.0 OE1 A:GLN261 4.9 22.9 1.0 CA A:PRO260 5.0 26.4 1.0

Iodine binding site 4 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 4 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I4 b:0.7 occ:1.00 NE2 A:GLN283 3.8 38.1 1.0 CD2 A:TYR282 3.9 46.7 1.0 CB A:MET279 4.1 33.8 1.0 CE A:MET279 4.1 52.1 1.0 CG A:MET279 4.2 37.4 1.0 O A:MET279 4.4 31.2 1.0 CE1 A:PHE274 4.4 53.3 1.0 CG A:GLN283 4.4 25.0 1.0 CA A:MET279 4.5 31.8 1.0 CE2 A:TYR282 4.5 50.5 1.0 CD A:GLN283 4.6 32.1 1.0 CZ A:PHE274 4.7 54.5 1.0 CG A:TYR282 4.7 45.4 1.0 CB A:TYR282 4.8 39.9 1.0 C A:MET279 4.9 30.1 1.0

Iodine binding site 5 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 5 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I5 b:0.9 occ:1.00 CB A:ASP294 4.2 36.2 1.0 CG1 A:ILE291 4.2 22.9 1.0 CG A:ASP294 4.3 41.1 1.0 OG A:SER317 4.4 36.7 1.0 CA A:ILE291 4.4 25.6 1.0 CB A:SER317 4.5 32.3 1.0 OD2 A:ASP294 4.5 42.0 1.0 O A:ASP290 4.5 32.5 1.0 N A:ILE291 4.5 24.1 1.0 C A:ASP290 4.5 28.9 1.0 CE A:LYS287 4.5 42.8 1.0 CB A:ASP290 4.5 31.4 1.0 NZ A:LYS287 4.6 47.9 1.0 O A:HOH133 4.7 46.7 1.0 NH1 A:ARG318 4.7 25.3 1.0 OD1 A:ASP294 4.8 44.8 1.0 NH2 A:ARG318 4.8 25.9 1.0 CB A:ILE291 5.0 22.4 1.0

Iodine binding site 6 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 6 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I7 b:0.8 occ:1.00 O A:HOH116 3.1 53.0 1.0 O A:HOH138 3.8 60.2 1.0 O A:HOH27 3.9 34.9 1.0 CD2 A:TYR384 4.3 23.1 1.0 CG A:TYR384 4.4 24.4 1.0 CE2 A:TYR384 4.5 24.1 1.0 NZ A:LYS335 4.6 33.1 1.0 CD A:LYS335 4.6 27.3 1.0 CD1 A:TYR384 4.6 24.3 1.0 CE A:LYS335 4.7 32.0 1.0 CZ A:TYR384 4.8 24.7 1.0 CE1 A:TYR384 4.8 23.5 1.0 CB A:TYR384 4.9 22.6 1.0

Iodine binding site 7 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 7 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I8 b:69.3 occ:1.00 CG2 A:THR190 4.1 33.9 1.0 CG2 A:ILE186 4.1 38.2 1.0 CD A:LYS189 4.1 57.7 1.0 O A:HOH126 4.2 48.2 1.0 CD A:LYS267 4.3 34.6 1.0 CG A:LYS189 4.4 50.4 1.0 CB A:LYS189 4.4 41.2 1.0 CA A:ILE186 4.4 35.0 1.0 O A:ILE186 4.5 35.4 1.0 CB A:ILE186 4.7 35.9 1.0 CG1 A:ILE186 4.7 37.9 1.0 NZ A:LYS267 4.7 45.5 1.0 O A:HOH70 4.7 36.0 1.0 C A:ILE186 5.0 34.0 1.0

Iodine binding site 8 out of 8 in the MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 8 of MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane within 5.0Å range: probe atom residue distance (Å) B Occ A:I9 b:47.3 occ:1.00 O A:LYS321 2.9 63.0 1.0 NH1 A:ARG187 3.5 28.7 1.0 C A:LYS321 3.7 56.5 1.0 CB A:TYR323 3.7 70.2 1.0 O A:HOH89 3.7 55.8 1.0 CD1 A:ILE184 3.8 49.4 1.0 N A:TYR323 4.0 63.7 1.0 CZ A:PHE359 4.0 45.9 1.0 CA A:LYS321 4.0 49.9 1.0 CD A:ARG187 4.3 26.0 1.0 CG1 A:ILE184 4.3 49.3 1.0 CE1 A:PHE359 4.3 50.9 1.0 CG A:LYS321 4.4 57.3 1.0 CA A:TYR323 4.5 65.5 1.0 CD2 A:LEU183 4.5 41.3 1.0 CZ A:ARG187 4.5 28.6 1.0 CG A:LEU183 4.6 42.4 1.0 O A:MET320 4.6 38.8 1.0 N A:ALA322 4.7 57.3 1.0 NE A:ARG187 4.8 27.5 1.0 CG2 A:VAL316 4.8 30.1 1.0 CB A:LYS321 4.9 54.1 1.0 CG A:TYR323 4.9 77.7 1.0 CB A:LEU183 5.0 42.4 1.0

D.Lupo, C.Vollmer, M.Deckers, D.U.Mick, I.Tews, I.Sinning, P.Rehling. MDM38 Is A 14-3-3-Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane. Traffic V. 12 1457 2011.
ISSN: ISSN 1398-9219
PubMed: 21718401
DOI: 10.1111/J.1600-0854.2011.01239.X