Iodine in PDB 4a3p: Structure of USP15 Dusp-Ubl Deletion Mutant

All present enzymatic activity of Structure of USP15 Dusp-Ubl Deletion Mutant:
3.4.19.12;

The structure of Structure of USP15 Dusp-Ubl Deletion Mutant, PDB code: 4a3p was solved by P.R.Elliott, H.Liu, M.W.Pastok, G.J.Grossmann, D.J.Rigden, M.J.Clague, S.Urbe, I.L.Barsukov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.20 / 1.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.950, 44.250, 56.150, 90.00, 104.33, 90.00
R / Rfree (%)	15.3 / 22.126

The binding sites of Iodine atom in the Structure of USP15 Dusp-Ubl Deletion Mutant (pdb code 4a3p). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Structure of USP15 Dusp-Ubl Deletion Mutant, PDB code: 4a3p:

Iodine binding site 1 out of 1 in the Structure of USP15 Dusp-Ubl Deletion Mutant


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Structure of USP15 Dusp-Ubl Deletion Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:I1224 b:19.3 occ:1.00 O A:HOH2101 3.6 29.6 1.0 O A:HOH2139 3.7 45.5 1.0 N A:LEU133 3.8 13.9 1.0 NH2 A:ARG115 3.8 17.3 1.0 N A:LEU79 3.9 17.6 1.0 CD A:ARG151 4.2 24.0 1.0 CA A:TYR132 4.3 18.4 1.0 CB A:LEU79 4.3 16.6 1.0 CB A:LEU133 4.3 12.8 1.0 NE A:ARG151 4.3 43.2 1.0 CG A:LEU79 4.3 16.5 1.0 O A:VAL131 4.4 18.4 1.0 CD1 A:TYR132 4.4 18.7 1.0 CA A:SER78 4.5 24.6 1.0 C A:TYR132 4.5 15.4 1.0 CD1 A:LEU79 4.5 17.1 1.0 CG A:LEU133 4.6 14.8 1.0 CA A:LEU133 4.6 13.9 1.0 C A:SER78 4.7 22.1 1.0 CA A:LEU79 4.7 16.8 1.0 CZ A:ARG115 4.8 14.7 1.0 CD1 A:LEU133 4.8 15.0 1.0 OG A:SER78 4.9 44.6 1.0 O A:LEU133 4.9 17.0 1.0 CB A:TYR132 5.0 19.5 1.0

P.R.Elliott, H.Liu, M.W.Pastok, G.J.Grossmann, D.J.Rigden, M.J.Clague, S.Urbe, I.L.Barsukov. Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains. Febs Lett. V. 585 3385 2011.
ISSN: ISSN 0014-5793
PubMed: 22001210
DOI: 10.1016/J.FEBSLET.2011.09.040