|
Atomistry » Iodine » PDB 442d-4dch » 4an2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iodine » PDB 442d-4dch » 4an2 » |
Iodine in PDB 4an2: Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs.Enzymatic activity of Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs.
All present enzymatic activity of Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs.:
2.7.12.2; Protein crystallography data
The structure of Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs., PDB code: 4an2
was solved by
K.D.Rice,
N.Aay,
N.K.Anand,
C.M.Blazey,
O.J.Bowles,
J.Bussenius,
S.Costanzo,
J.K.Curtis,
S.C.Defina,
L.Dubenko,
S.Engst,
A.A.Joshi,
A.R.Kennedy,
A.I.Kim,
E.S.Koltun,
J.C.Lougheed,
J.C.L.Manalo,
J.F.Martini,
J.M.Nuss,
C.J.Peto,
T.H.Tsang,
P.Yu,
S.Johnston,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4an2:
The structure of Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs. also contains other interesting chemical elements:
Iodine Binding Sites:
The binding sites of Iodine atom in the Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs.
(pdb code 4an2). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs., PDB code: 4an2: Iodine binding site 1 out of 1 in 4an2Go back to Iodine Binding Sites List in 4an2
Iodine binding site 1 out
of 1 in the Crystal Structures of Human MEK1 with Carboxamide-Based Allosteric Inhibitor XL518 (Gdc-0973), or Related Analogs.
Mono view Stereo pair view
Reference:
K.D.Rice,
N.Aay,
N.K.Anand,
C.M.Blazey,
O.J.Bowles,
J.Bussenius,
S.Costanzo,
J.K.Curtis,
S.C.Defina,
L.Dubenko,
S.Engst,
A.A.Joshi,
A.R.Kennedy,
A.I.Kim,
E.S.Koltun,
J.C.Lougheed,
J.C.L.Manalo,
J.F.Martini,
J.M.Nuss,
C.J.Peto,
T.H.Tsang,
P.Yu,
S.Johnston.
Novel Carboxamide-Based Allosteric Mek Inhibitors: Discovery and Optimization Efforts Toward XL518 (Gdc-0973) Acs Med.Chem.Lett. V. 3 416 2012.
Page generated: Sun Dec 13 19:31:50 2020
ISSN: ISSN 1948-5875 PubMed: 24900486 DOI: 10.1021/ML300049D |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |