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Atomistry » Iodine » PDB 4dgh-4hjh » 4frk | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iodine » PDB 4dgh-4hjh » 4frk » |
Iodine in PDB 4frk: Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11AEnzymatic activity of Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A
All present enzymatic activity of Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A:
3.4.23.46; Protein crystallography data
The structure of Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A, PDB code: 4frk
was solved by
D.A.Whittington,
A.M.Long,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iodine Binding Sites:
The binding sites of Iodine atom in the Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A
(pdb code 4frk). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total 4 binding sites of Iodine where determined in the Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A, PDB code: 4frk: Jump to Iodine binding site number: 1; 2; 3; 4; Iodine binding site 1 out of 4 in 4frkGo back to Iodine Binding Sites List in 4frk
Iodine binding site 1 out
of 4 in the Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A
Mono view Stereo pair view
Iodine binding site 2 out of 4 in 4frkGo back to Iodine Binding Sites List in 4frk
Iodine binding site 2 out
of 4 in the Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A
Mono view Stereo pair view
Iodine binding site 3 out of 4 in 4frkGo back to Iodine Binding Sites List in 4frk
Iodine binding site 3 out
of 4 in the Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A
Mono view Stereo pair view
Iodine binding site 4 out of 4 in 4frkGo back to Iodine Binding Sites List in 4frk
Iodine binding site 4 out
of 4 in the Crystal Structure of BACE1 in Complex with Aminooxazoline Xanthene 11A
Mono view Stereo pair view
Reference:
H.Huang,
D.S.La,
A.C.Cheng,
D.A.Whittington,
V.F.Patel,
K.Chen,
T.A.Dineen,
O.Epstein,
R.Graceffa,
D.Hickman,
Y.H.Kiang,
S.Louie,
Y.Luo,
R.C.Wahl,
P.H.Wen,
S.Wood,
R.T.Fremeau.
Structure- and Property-Based Design of Aminooxazoline Xanthenes As Selective, Orally Efficacious, and Cns Penetrable Bace Inhibitors For the Treatment of Alzheimer'S Disease. J.Med.Chem. V. 55 9156 2012.
Page generated: Sun Dec 13 19:32:39 2020
ISSN: ISSN 0022-2623 PubMed: 22928914 DOI: 10.1021/JM300598E |
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