Iodine in PDB 4m73: Mutant Structure of Methyltransferase From Streptomyces Hygroscopicus

The structure of Mutant Structure of Methyltransferase From Streptomyces Hygroscopicus, PDB code: 4m73 was solved by Y.C.Liu, X.W.Zou, H.C.Chan, C.J.Huang, T.L.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.05 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	60.989, 96.810, 135.404, 90.00, 90.00, 90.00
R / Rfree (%)	15.2 / 21.1

The structure of Mutant Structure of Methyltransferase From Streptomyces Hygroscopicus also contains other interesting chemical elements:

Iron	(Fe)	2 atoms
Calcium	(Ca)	13 atoms

The binding sites of Iodine atom in the Mutant Structure of Methyltransferase From Streptomyces Hygroscopicus (pdb code 4m73). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Mutant Structure of Methyltransferase From Streptomyces Hygroscopicus, PDB code: 4m73:

Iodine binding site 1 out of 1 in the Mutant Structure of Methyltransferase From Streptomyces Hygroscopicus


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Mutant Structure of Methyltransferase From Streptomyces Hygroscopicus within 5.0Å range: probe atom residue distance (Å) B Occ A:I411 b:32.3 occ:1.00 O A:HOH501 3.2 55.9 1.0 N A:ASP217 3.6 27.4 1.0 O A:HOH758 3.7 36.0 1.0 O A:HOH670 3.8 40.4 1.0 OG1 A:THR220 3.9 19.3 1.0 OE1 A:GLN223 4.0 36.6 1.0 CA A:GLY216 4.1 23.6 1.0 CB A:GLN223 4.1 25.9 1.0 CB A:ASP217 4.1 23.8 1.0 CG2 A:VAL224 4.2 20.9 1.0 O A:THR220 4.3 17.2 1.0 NH2 A:ARG215 4.3 43.1 1.0 C A:GLY216 4.4 24.9 1.0 CA A:ASP217 4.5 22.3 1.0 O A:GLN223 4.6 21.8 1.0 C A:GLN223 4.6 22.0 1.0 O A:ASP217 4.7 19.0 1.0 N A:VAL224 4.9 19.5 1.0 CD A:GLN223 4.9 29.4 1.0 CA A:VAL224 4.9 22.0 1.0 O A:HOH703 5.0 42.9 1.0

X.W.Zou, Y.C.Liu, N.S.Hsu, C.J.Huang, S.Y.Lyu, H.C.Chan, C.Y.Chang, H.W.Yeh, K.H.Lin, C.J.Wu, M.D.Tsai, T.L.Li. Structure and Mechanism of A Nonhaem-Iron Sam-Dependent C-Methyltransferase and Its Engineering to A Hydratase and An O-Methyltransferase Acta Crystallogr.,Sect.D V. 70 1549 2014.
ISSN: ISSN 0907-4449
PubMed: 24914966
DOI: 10.1107/S1399004714005239