Iodine in PDB 5ems: Crystal Structure of An Iodinated Insulin Analog
Protein crystallography data
The structure of Crystal Structure of An Iodinated Insulin Analog, PDB code: 5ems
was solved by
M.C.Lawrence,
V.Pandyarajan,
Z.Wan,
M.A.Weiss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 40.85 / 2.30 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 46.430, 61.630, 58.580, 90.00, 111.38, 90.00 |
| R / Rfree (%) | 16.3 / 23.3 |
Other elements in 5ems:
The structure of Crystal Structure of An Iodinated Insulin Analog also contains other interesting chemical elements:
| Chlorine | (Cl) | 2 atoms |
| Zinc | (Zn) | 2 atoms |
Iodine Binding Sites:
The binding sites of Iodine atom in the Crystal Structure of An Iodinated Insulin Analog
(pdb code 5ems). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total 6 binding sites of Iodine where determined in the Crystal Structure of An Iodinated Insulin Analog, PDB code: 5ems:
Jump to Iodine binding site number: 1; 2; 3; 4; 5; 6;
In total 6 binding sites of Iodine where determined in the Crystal Structure of An Iodinated Insulin Analog, PDB code: 5ems:
Jump to Iodine binding site number: 1; 2; 3; 4; 5; 6;
Iodine binding site 1 out of 6 in 5ems
Go back to
Iodine Binding Sites List in 5ems
Iodine binding site 1 out
of 6 in the Crystal Structure of An Iodinated Insulin Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iodine with other atoms in the I binding
site number 1 of Crystal Structure of An Iodinated Insulin Analog within 5.0Å range:
|
Iodine binding site 2 out of 6 in 5ems
Go back to
Iodine Binding Sites List in 5ems
Iodine binding site 2 out
of 6 in the Crystal Structure of An Iodinated Insulin Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iodine with other atoms in the I binding
site number 2 of Crystal Structure of An Iodinated Insulin Analog within 5.0Å range:
|
Iodine binding site 3 out of 6 in 5ems
Go back to
Iodine Binding Sites List in 5ems
Iodine binding site 3 out
of 6 in the Crystal Structure of An Iodinated Insulin Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iodine with other atoms in the I binding
site number 3 of Crystal Structure of An Iodinated Insulin Analog within 5.0Å range:
|
Iodine binding site 4 out of 6 in 5ems
Go back to
Iodine Binding Sites List in 5ems
Iodine binding site 4 out
of 6 in the Crystal Structure of An Iodinated Insulin Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iodine with other atoms in the I binding
site number 4 of Crystal Structure of An Iodinated Insulin Analog within 5.0Å range:
|
Iodine binding site 5 out of 6 in 5ems
Go back to
Iodine Binding Sites List in 5ems
Iodine binding site 5 out
of 6 in the Crystal Structure of An Iodinated Insulin Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iodine with other atoms in the I binding
site number 5 of Crystal Structure of An Iodinated Insulin Analog within 5.0Å range:
|
Iodine binding site 6 out of 6 in 5ems
Go back to
Iodine Binding Sites List in 5ems
Iodine binding site 6 out
of 6 in the Crystal Structure of An Iodinated Insulin Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iodine with other atoms in the I binding
site number 6 of Crystal Structure of An Iodinated Insulin Analog within 5.0Å range:
|
Reference:
K.El Hage,
V.Pandyarajan,
N.B.Phillips,
B.J.Smith,
J.G.Menting,
J.Whittaker,
M.C.Lawrence,
M.Meuwly,
M.A.Weiss.
Extending Halogen-Based Medicinal Chemistry to Proteins: Iodo-Insulin As A Case Study. J. Biol. Chem. V. 291 27023 2016.
ISSN: ESSN 1083-351X
PubMed: 27875310
DOI: 10.1074/JBC.M116.761015
Page generated: Sun Dec 13 19:39:08 2020
ISSN: ESSN 1083-351X
PubMed: 27875310
DOI: 10.1074/JBC.M116.761015
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