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Atomistry » Iodine » PDB 5enk-5kio » 5enm | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iodine » PDB 5enk-5kio » 5enm » |
Iodine in PDB 5enm: Compound 10Enzymatic activity of Compound 10
All present enzymatic activity of Compound 10:
3.4.23.46; Protein crystallography data
The structure of Compound 10, PDB code: 5enm
was solved by
H.A.Lewis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5enm:
The structure of Compound 10 also contains other interesting chemical elements:
Iodine Binding Sites:
The binding sites of Iodine atom in the Compound 10
(pdb code 5enm). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Compound 10, PDB code: 5enm: Iodine binding site 1 out of 1 in 5enmGo back to Iodine Binding Sites List in 5enm
Iodine binding site 1 out
of 1 in the Compound 10
Mono view Stereo pair view
Reference:
Y.J.Wu,
J.Guernon,
F.Yang,
L.Snyder,
J.Shi,
A.Mcclure,
R.Rajamani,
H.Park,
A.Ng,
H.Lewis,
C.Chang,
D.Camac,
J.H.Toyn,
M.K.Ahlijanian,
C.F.Albright,
J.E.Macor,
L.A.Thompson.
Targeting the BACE1 Active Site Flap Leads to A Potent Inhibitor That Elicits Robust Brain A Beta Reduction in Rodents. Acs Med.Chem.Lett. V. 7 271 2016.
Page generated: Sun Dec 13 19:39:09 2020
ISSN: ISSN 1948-5875 PubMed: 26985314 DOI: 10.1021/ACSMEDCHEMLETT.5B00432 |
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