Iodine in PDB 5mph: Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily

The structure of Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily, PDB code: 5mph was solved by Q.Ming, Y.Roske, A.Schuetz, K.Walentin, I.Ibraimi, K.M.Schmidt-Ott, U.Heinemann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.02 / 2.34
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	106.752, 106.752, 115.634, 90.00, 90.00, 120.00
R / Rfree (%)	19.2 / 22.9

The binding sites of Iodine atom in the Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily (pdb code 5mph). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily, PDB code: 5mph:
Jump to Iodine binding site number: 1; 2;

Iodine binding site 1 out of 2 in the Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily within 5.0Å range: probe atom residue distance (Å) B Occ A:I501 b:0.8 occ:1.00 NH1 A:ARG263 3.3 0.1 1.0 OG A:SER269 3.6 0.4 1.0 N A:THR270 3.7 0.3 1.0 CA A:SER269 3.9 0.9 1.0 CG2 A:THR270 3.9 98.4 1.0 NH2 A:ARG263 4.0 70.4 1.0 CZ A:ARG263 4.1 81.5 1.0 O A:ASP268 4.2 92.8 1.0 O A:HOH607 4.2 85.9 1.0 CE A:LYS461 4.2 82.2 1.0 CB A:SER269 4.3 0.4 1.0 C A:SER269 4.3 0.9 1.0 NZ A:LYS461 4.5 92.6 1.0 I A:IOD502 4.5 0.5 1.0 CB A:THR270 4.7 0.1 1.0 CA A:THR270 4.8 1.0 1.0 N A:SER269 4.9 92.0 1.0 C A:ASP268 5.0 84.3 1.0

Iodine binding site 2 out of 2 in the Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Structural Basis of Gene Regulation By the Grainyhead Transcription Factor Superfamily within 5.0Å range: probe atom residue distance (Å) B Occ A:I502 b:0.5 occ:1.00 NH2 A:ARG263 3.2 70.4 1.0 O A:HOH631 3.3 84.8 1.0 CG2 A:THR270 3.7 98.4 1.0 CZ A:ARG263 4.5 81.5 1.0 I A:IOD501 4.5 0.8 1.0 CE A:LYS461 4.6 82.2 1.0 CB A:THR270 4.7 0.1 1.0 O A:HOH619 4.8 79.0 1.0 NZ A:LYS260 4.9 0.6 1.0

Q.Ming, Y.Roske, A.Schuetz, K.Walentin, I.Ibraimi, K.M.Schmidt-Ott, U.Heinemann. Structural Basis of Gene Regulation By the Grainyhead/CP2 Transcription Factor Family. Nucleic Acids Res. V. 46 2082 2018.
ISSN: ESSN 1362-4962
PubMed: 29309642
DOI: 10.1093/NAR/GKX1299