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Atomistry » Iodine » PDB 5nje-5say » 5o1c | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iodine » PDB 5nje-5say » 5o1c » |
Iodine in PDB 5o1c: P53 Cancer Mutant Y220C in Complex with Compound MB184Protein crystallography data
The structure of P53 Cancer Mutant Y220C in Complex with Compound MB184, PDB code: 5o1c
was solved by
A.C.Joerger,
M.G.J.Baud,
M.R.Bauer,
A.R.Fersht,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5o1c:
The structure of P53 Cancer Mutant Y220C in Complex with Compound MB184 also contains other interesting chemical elements:
Iodine Binding Sites:
The binding sites of Iodine atom in the P53 Cancer Mutant Y220C in Complex with Compound MB184
(pdb code 5o1c). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the P53 Cancer Mutant Y220C in Complex with Compound MB184, PDB code: 5o1c: Jump to Iodine binding site number: 1; 2; Iodine binding site 1 out of 2 in 5o1cGo back to![]() ![]()
Iodine binding site 1 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Compound MB184
![]() Mono view ![]() Stereo pair view
Iodine binding site 2 out of 2 in 5o1cGo back to![]() ![]()
Iodine binding site 2 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Compound MB184
![]() Mono view ![]() Stereo pair view
Reference:
M.G.J.Baud,
M.R.Bauer,
L.Verduci,
F.A.Dingler,
K.J.Patel,
D.Horil Roy,
A.C.Joerger,
A.R.Fersht.
Aminobenzothiazole Derivatives Stabilize the Thermolabile P53 Cancer Mutant Y220C and Show Anticancer Activity in P53-Y220C Cell Lines. Eur J Med Chem V. 152 101 2018.
Page generated: Sun Aug 11 21:40:05 2024
ISSN: ISSN 1768-3254 PubMed: 29702446 DOI: 10.1016/J.EJMECH.2018.04.035 |
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