Iodine in PDB 5ug6: Perforin C2 Domain - T431D

The structure of Perforin C2 Domain - T431D, PDB code: 5ug6 was solved by R.H.P.Law, P.J.Conroy, I.Voskoboinik, J.C.Whisstock, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.01 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	27.774, 66.027, 74.867, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 22.2

The binding sites of Iodine atom in the Perforin C2 Domain - T431D (pdb code 5ug6). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Perforin C2 Domain - T431D, PDB code: 5ug6:

Iodine binding site 1 out of 1 in the Perforin C2 Domain - T431D


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Perforin C2 Domain - T431D within 5.0Å range: probe atom residue distance (Å) B Occ A:I601 b:19.3 occ:1.00 O A:HOH701 2.5 20.5 1.0 OD2 A:ASP465 2.5 16.8 1.0 O A:HOH728 2.8 22.2 1.0 CG A:ASP465 3.6 19.6 1.0 CB A:ASP465 4.1 18.4 1.0 NE2 A:HIS415 4.4 16.8 1.0 OE2 A:GLU467 4.4 23.9 1.0 CE1 A:HIS415 4.6 16.5 1.0 OD1 A:ASP465 4.6 19.0 1.0 OE1 A:GLU467 4.7 25.7 1.0

A.J.Brennan, R.H.P.Law, P.J.Conroy, T.Noori, N.Lukoyanova, H.Saibil, H.Yagita, A.Ciccone, S.Verschoor, J.C.Whisstock, J.A.Trapani, I.Voskoboinik. Perforin Proteostasis Is Regulated Through Its C2 Domain: Supra-Physiological Cell Death Mediated By T431D-Perforin. Cell Death Differ. V. 25 1517 2018.
ISSN: ISSN 1476-5403
PubMed: 29416110
DOI: 10.1038/S41418-018-0057-Z