Iodine in PDB 6axy: Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein

The structure of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein, PDB code: 6axy was solved by A.T.Gres, K.A.Kirby, S.G.Sarafianos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.96 / 2.78
Space group	P 6
Cell size a, b, c (Å), α, β, γ (°)	91.915, 91.915, 57.919, 90.00, 90.00, 120.00
R / Rfree (%)	21.3 / 26

The structure of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein also contains other interesting chemical elements:

Chlorine

(Cl)

9 atoms

The binding sites of Iodine atom in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein (pdb code 6axy). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 7 binding sites of Iodine where determined in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein, PDB code: 6axy:
Jump to Iodine binding site number: 1; 2; 3; 4; 5; 6; 7;

Iodine binding site 1 out of 7 in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:I301 b:77.0 occ:1.00 N A:LYS158 3.6 77.2 1.0 N A:GLU159 3.8 71.7 1.0 CD A:PRO157 3.8 78.5 1.0 CA A:GLY156 3.9 72.8 1.0 CB A:LYS158 3.9 80.2 1.0 N A:PRO157 4.0 76.3 1.0 C A:GLY156 4.0 73.7 1.0 CA A:LYS158 4.0 77.1 1.0 C A:LYS158 4.1 74.1 1.0 CB A:GLU159 4.3 68.3 1.0 CA A:GLU159 4.4 69.5 1.0 CG A:PRO157 4.4 81.3 1.0 O A:GLY156 4.6 71.9 1.0 C A:PRO157 4.7 77.3 1.0 CA A:PRO157 4.9 77.4 1.0 O A:LYS158 4.9 74.2 1.0 N A:GLY156 4.9 70.5 1.0 CG A:LYS158 4.9 83.9 1.0

Iodine binding site 2 out of 7 in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:I302 b:68.8 occ:0.81 NH1 A:ARG173 3.7 62.6 1.0 OE1 A:GLU35 3.8 84.7 1.0 CD A:ARG173 3.8 60.2 1.0 CG A:LYS170 3.9 62.2 1.0 CD A:LYS170 4.1 63.8 1.0 CE A:LYS170 4.2 66.3 1.0 CD A:PRO34 4.2 80.5 1.0 CG A:PRO34 4.3 81.9 1.0 CB A:LYS170 4.5 60.0 1.0 OG A:SER33 4.5 81.0 1.0 CA A:LYS170 4.6 58.9 1.0 CZ A:ARG173 4.6 62.6 1.0 NE A:ARG173 4.6 61.4 1.0 CB A:PRO34 4.7 82.1 1.0 CB A:ARG173 4.8 59.4 1.0 CD A:GLU35 4.9 84.2 1.0 O A:LYS170 4.9 60.2 1.0 CG A:ARG173 4.9 60.1 1.0

Iodine binding site 3 out of 7 in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 3 of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:I303 b:90.4 occ:0.74 CE A:MET144 3.6 87.2 1.0 CG A:MET144 4.1 80.0 1.0 CE1 A:TYR145 4.5 82.3 1.0 CD1 A:TYR145 4.6 80.2 1.0 SD A:MET144 4.6 82.5 1.0 O A:MET144 4.8 77.0 1.0

Iodine binding site 4 out of 7 in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 4 of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:I304 b:83.3 occ:0.58 OG A:SER41 3.6 76.6 1.0 CG2 A:ILE37 3.9 78.5 1.0 O A:ILE37 4.0 74.8 1.0 CA A:PRO38 4.0 78.9 1.0 N A:PRO38 4.1 77.2 1.0 CB A:SER41 4.1 76.4 1.0 C A:ILE37 4.1 75.8 1.0 CD A:PRO38 4.6 78.7 1.0 CG A:PRO38 4.6 81.7 1.0 CB A:ILE37 4.7 77.4 1.0 CB A:PRO38 4.8 81.4 1.0 CL A:CL309 4.8 61.0 1.0 CG2 A:ILE135 4.9 61.8 1.0 CD1 A:ILE135 4.9 63.0 1.0

Iodine binding site 5 out of 7 in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 5 of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:I305 b:0.2 occ:0.70 CB A:ALA124 3.8 83.6 1.0 CH2 A:TRP80 4.0 70.5 1.0 CA A:ALA124 4.0 84.7 1.0 CZ2 A:TRP80 4.1 70.8 1.0 CD1 A:ILE129 4.1 71.5 1.0 CG A:PRO99 4.3 83.6 1.0 CD A:PRO125 4.3 84.2 1.0 C A:ALA124 4.4 82.5 1.0 N A:PRO125 4.7 82.6 1.0 CD A:PRO99 4.9 84.8 1.0 O A:ALA124 4.9 80.7 1.0

Iodine binding site 6 out of 7 in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 6 of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:I306 b:82.7 occ:0.54 CA A:ARG173 3.8 59.6 1.0 CG A:LEU172 3.9 58.0 1.0 N A:ARG173 3.9 58.8 1.0 NZ A:LYS182 4.0 69.5 1.0 CD A:LYS182 4.0 67.9 1.0 CD2 A:LEU172 4.1 57.3 1.0 C A:LEU172 4.1 58.8 1.0 O A:LEU172 4.1 59.2 1.0 CB A:LEU172 4.3 57.5 1.0 CB A:ARG173 4.4 59.4 1.0 O A:TYR169 4.5 57.7 1.0 CG A:ARG173 4.6 60.1 1.0 CE A:LYS182 4.6 69.5 1.0 CA A:LEU172 4.9 58.4 1.0 CD1 A:TYR169 5.0 55.4 1.0

Iodine binding site 7 out of 7 in the Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 7 of Structure of the V11I/T58A/I124A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:I307 b:0.7 occ:0.71 NH2 A:ARG18 3.8 0.6 1.0 NE A:ARG18 3.9 99.9 1.0 CB A:ALA22 4.3 79.7 1.0 CZ A:ARG18 4.3 0.9 1.0 O A:ARG18 4.6 86.1 1.0

M.Novikova, A.T.Gres, K.A.Kirby, S.G.Sarafianos, E.O.Freed. Identification of A Novel Element in Hiv-1 Capsid Critical For Assembly and Maturation To Be Published.