Iodine in PDB 6spw: Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Enzymatic activity of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
All present enzymatic activity of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140:
2.7.11.1;
Protein crystallography data
The structure of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140, PDB code: 6spw
was solved by
K.Niefind,
A.Schnitzler,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
42.59 /
1.60
|
Space group
|
P 21 21 21
|
Cell size a, b, c (Å), α, β, γ (°)
|
47.503,
85.171,
90.432,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
16.5 /
19.6
|
Other elements in 6spw:
The structure of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 also contains other interesting chemical elements:
Iodine Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Iodine atom in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
(pdb code 6spw). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total 12 binding sites of Iodine where determined in the
Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140, PDB code: 6spw:
Jump to Iodine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Iodine binding site 1 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 1 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 1 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:I101
b:22.3
occ:1.00
|
IAW
|
B:A0Z101
|
0.0
|
22.3
|
1.0
|
CCO
|
B:A0Z101
|
2.1
|
21.4
|
1.0
|
CCQ
|
B:A0Z101
|
3.1
|
20.9
|
1.0
|
CCP
|
B:A0Z101
|
3.1
|
28.4
|
1.0
|
O
|
A:GLU114
|
3.3
|
15.5
|
1.0
|
IAY
|
B:A0Z101
|
3.5
|
29.0
|
1.0
|
IAX
|
B:A0Z101
|
3.6
|
26.5
|
1.0
|
CD1
|
A:ILE95
|
3.8
|
13.1
|
1.0
|
CG2
|
A:VAL66
|
3.8
|
14.4
|
1.0
|
CB
|
A:VAL66
|
3.9
|
12.2
|
1.0
|
CG1
|
A:VAL66
|
4.1
|
12.1
|
1.0
|
CG1
|
A:ILE95
|
4.2
|
12.9
|
1.0
|
N
|
A:VAL116
|
4.2
|
21.1
|
1.0
|
CB
|
A:PHE113
|
4.4
|
11.2
|
1.0
|
CCR
|
B:A0Z101
|
4.4
|
36.3
|
1.0
|
CG2
|
A:VAL116
|
4.4
|
25.0
|
1.0
|
CCS
|
B:A0Z101
|
4.4
|
27.3
|
1.0
|
C
|
A:GLU114
|
4.5
|
16.4
|
1.0
|
CB
|
A:VAL116
|
4.6
|
26.8
|
1.0
|
CA
|
A:HIS115
|
4.7
|
20.5
|
1.0
|
C
|
A:HIS115
|
4.7
|
19.7
|
1.0
|
CG2
|
A:ILE174
|
5.0
|
18.5
|
1.0
|
CCT
|
B:A0Z101
|
5.0
|
30.7
|
1.0
|
CG
|
A:PHE113
|
5.0
|
12.6
|
1.0
|
|
Iodine binding site 2 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 2 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 2 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:I101
b:26.5
occ:1.00
|
IAX
|
B:A0Z101
|
0.0
|
26.5
|
1.0
|
CCP
|
B:A0Z101
|
2.1
|
28.4
|
1.0
|
O
|
A:VAL116
|
3.0
|
28.4
|
1.0
|
CCR
|
B:A0Z101
|
3.0
|
36.3
|
1.0
|
CCO
|
B:A0Z101
|
3.0
|
21.4
|
1.0
|
IAZ
|
B:A0Z101
|
3.5
|
60.3
|
1.0
|
IAW
|
B:A0Z101
|
3.6
|
22.3
|
1.0
|
C
|
A:VAL116
|
4.0
|
25.2
|
1.0
|
CB
|
A:VAL116
|
4.1
|
26.8
|
1.0
|
N
|
A:VAL116
|
4.1
|
21.1
|
1.0
|
CD1
|
A:LEU45
|
4.1
|
29.1
|
1.0
|
SD
|
A:MET163
|
4.3
|
36.6
|
1.0
|
CA
|
A:VAL116
|
4.3
|
22.2
|
1.0
|
CCQ
|
B:A0Z101
|
4.3
|
20.9
|
1.0
|
CG2
|
A:VAL66
|
4.4
|
14.4
|
1.0
|
CCT
|
B:A0Z101
|
4.4
|
30.7
|
1.0
|
O
|
A:HOH732
|
4.4
|
49.6
|
1.0
|
CG
|
A:MET163
|
4.6
|
29.0
|
1.0
|
CB
|
A:ASN118
|
4.8
|
48.4
|
1.0
|
O
|
A:HOH769
|
4.9
|
21.4
|
1.0
|
CCS
|
B:A0Z101
|
4.9
|
27.3
|
1.0
|
N
|
A:ASN118
|
5.0
|
39.1
|
1.0
|
CG1
|
A:VAL116
|
5.0
|
29.1
|
1.0
|
|
Iodine binding site 3 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 3 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 3 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:I101
b:29.0
occ:1.00
|
IAY
|
B:A0Z101
|
0.0
|
29.0
|
1.0
|
CCQ
|
B:A0Z101
|
2.1
|
20.9
|
1.0
|
O
|
A:HOH737
|
2.7
|
14.5
|
1.0
|
CCO
|
B:A0Z101
|
3.0
|
21.4
|
1.0
|
CCS
|
B:A0Z101
|
3.0
|
27.3
|
1.0
|
CD1
|
A:PHE113
|
3.4
|
16.5
|
1.0
|
NBS
|
B:A0Z101
|
3.5
|
29.1
|
1.0
|
IAW
|
B:A0Z101
|
3.5
|
22.3
|
1.0
|
CE1
|
A:PHE113
|
3.6
|
12.6
|
1.0
|
CG
|
A:PHE113
|
3.7
|
12.6
|
1.0
|
CZ
|
A:PHE113
|
4.1
|
12.7
|
1.0
|
CD2
|
A:PHE113
|
4.2
|
10.6
|
1.0
|
CB
|
A:PHE113
|
4.3
|
11.2
|
1.0
|
CCP
|
B:A0Z101
|
4.3
|
28.4
|
1.0
|
CCT
|
B:A0Z101
|
4.3
|
30.7
|
1.0
|
CE2
|
A:PHE113
|
4.3
|
11.5
|
1.0
|
CG1
|
A:VAL66
|
4.4
|
12.1
|
1.0
|
CG1
|
A:ILE95
|
4.5
|
12.9
|
1.0
|
CG2
|
A:ILE174
|
4.8
|
18.5
|
1.0
|
CBA
|
B:A0Z101
|
4.8
|
30.7
|
1.0
|
CD
|
A:LYS68
|
4.8
|
29.7
|
1.0
|
CCR
|
B:A0Z101
|
4.8
|
36.3
|
1.0
|
CB
|
A:ILE174
|
4.9
|
15.6
|
1.0
|
|
Iodine binding site 4 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 4 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 4 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:I101
b:60.3
occ:1.00
|
IAZ
|
B:A0Z101
|
0.0
|
60.3
|
1.0
|
CCR
|
B:A0Z101
|
2.2
|
36.3
|
1.0
|
O
|
A:HOH769
|
2.3
|
21.4
|
1.0
|
CCP
|
B:A0Z101
|
3.1
|
28.4
|
1.0
|
CCT
|
B:A0Z101
|
3.1
|
30.7
|
1.0
|
CBL
|
B:A0Z101
|
3.4
|
38.9
|
1.0
|
IAX
|
B:A0Z101
|
3.5
|
26.5
|
1.0
|
NDB
|
B:A0Z101
|
3.6
|
32.4
|
1.0
|
SD
|
A:MET163
|
3.9
|
36.6
|
1.0
|
CB
|
A:LEU45
|
4.3
|
24.0
|
1.0
|
CCS
|
B:A0Z101
|
4.4
|
27.3
|
1.0
|
CCO
|
B:A0Z101
|
4.4
|
21.4
|
1.0
|
O
|
A:HOH732
|
4.5
|
49.6
|
1.0
|
CD1
|
A:LEU45
|
4.7
|
29.1
|
1.0
|
CBI
|
B:A0Z101
|
4.8
|
48.6
|
1.0
|
CE
|
A:MET163
|
4.8
|
36.6
|
1.0
|
O
|
A:LEU45
|
4.9
|
34.8
|
1.0
|
CBA
|
B:A0Z101
|
4.9
|
30.7
|
1.0
|
CCQ
|
B:A0Z101
|
4.9
|
20.9
|
1.0
|
CG1
|
A:VAL53
|
5.0
|
18.7
|
1.0
|
|
Iodine binding site 5 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 5 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 5 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:I101
b:25.1
occ:1.00
|
IAW
|
C:A0Z101
|
0.0
|
25.1
|
1.0
|
CCO
|
C:A0Z101
|
2.1
|
22.0
|
1.0
|
CCQ
|
C:A0Z101
|
3.0
|
20.6
|
1.0
|
CCP
|
C:A0Z101
|
3.0
|
25.2
|
1.0
|
IAX
|
C:A0Z101
|
3.5
|
27.5
|
1.0
|
IAY
|
C:A0Z101
|
3.6
|
22.9
|
1.0
|
CG2
|
A:VAL101
|
3.6
|
16.6
|
1.0
|
CB
|
A:ALA110
|
4.0
|
14.5
|
1.0
|
OE1
|
A:GLN36
|
4.1
|
45.4
|
1.0
|
CG1
|
A:VAL67
|
4.2
|
21.7
|
1.0
|
CCR
|
C:A0Z101
|
4.3
|
39.9
|
1.0
|
CB
|
A:GLN36
|
4.3
|
26.1
|
1.0
|
CCS
|
C:A0Z101
|
4.4
|
24.5
|
1.0
|
CB
|
A:VAL101
|
4.8
|
16.2
|
1.0
|
CA
|
A:GLN36
|
4.9
|
20.6
|
1.0
|
CCT
|
C:A0Z101
|
4.9
|
31.9
|
1.0
|
O
|
A:GLN36
|
4.9
|
18.3
|
1.0
|
|
Iodine binding site 6 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 6 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 6 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:I101
b:27.5
occ:1.00
|
IAX
|
C:A0Z101
|
0.0
|
27.5
|
1.0
|
CCP
|
C:A0Z101
|
2.2
|
25.2
|
1.0
|
CCO
|
C:A0Z101
|
3.1
|
22.0
|
1.0
|
CCR
|
C:A0Z101
|
3.1
|
39.9
|
1.0
|
O
|
A:THR108
|
3.3
|
21.9
|
1.0
|
IAZ
|
C:A0Z101
|
3.3
|
66.4
|
1.0
|
IAW
|
C:A0Z101
|
3.5
|
25.1
|
1.0
|
CG2
|
A:THR108
|
4.2
|
25.8
|
1.0
|
C
|
A:THR108
|
4.2
|
21.1
|
1.0
|
CB
|
A:THR108
|
4.3
|
27.7
|
1.0
|
CB
|
A:ALA110
|
4.3
|
14.5
|
1.0
|
CG2
|
A:ILE69
|
4.3
|
27.4
|
1.0
|
N
|
A:ASP103
|
4.3
|
24.3
|
1.0
|
CB
|
A:ASP103
|
4.3
|
27.1
|
1.0
|
CCQ
|
C:A0Z101
|
4.4
|
20.6
|
1.0
|
CCT
|
C:A0Z101
|
4.4
|
31.9
|
1.0
|
OE1
|
A:GLN36
|
4.4
|
45.4
|
1.0
|
O
|
A:PRO109
|
4.5
|
20.8
|
1.0
|
C
|
A:PRO109
|
4.6
|
18.2
|
1.0
|
CG1
|
A:ILE69
|
4.6
|
22.7
|
1.0
|
CD1
|
A:ILE69
|
4.8
|
28.5
|
1.0
|
N
|
A:ALA110
|
4.9
|
16.0
|
1.0
|
CA
|
A:THR108
|
4.9
|
25.4
|
1.0
|
CA
|
A:ASP103
|
4.9
|
25.2
|
1.0
|
CCS
|
C:A0Z101
|
4.9
|
24.5
|
1.0
|
N
|
A:PRO109
|
5.0
|
20.8
|
1.0
|
|
Iodine binding site 7 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 7 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 7 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:I101
b:22.9
occ:1.00
|
IAY
|
C:A0Z101
|
0.0
|
22.9
|
1.0
|
CCQ
|
C:A0Z101
|
2.1
|
20.6
|
1.0
|
CCS
|
C:A0Z101
|
3.0
|
24.5
|
1.0
|
CCO
|
C:A0Z101
|
3.1
|
22.0
|
1.0
|
O
|
A:TYR39
|
3.2
|
16.9
|
1.0
|
NBS
|
C:A0Z101
|
3.4
|
23.6
|
1.0
|
IAW
|
C:A0Z101
|
3.6
|
25.1
|
1.0
|
O
|
A:HOH573
|
3.6
|
31.0
|
1.0
|
C
|
A:TYR39
|
3.7
|
15.2
|
1.0
|
CB
|
A:TYR39
|
4.0
|
13.3
|
1.0
|
CA
|
A:GLN40
|
4.1
|
12.6
|
1.0
|
CD2
|
A:LEU41
|
4.1
|
16.9
|
1.0
|
N
|
A:GLN40
|
4.2
|
13.6
|
1.0
|
N
|
A:LEU41
|
4.2
|
13.9
|
1.0
|
CG
|
A:LEU41
|
4.2
|
16.6
|
1.0
|
CCT
|
C:A0Z101
|
4.3
|
31.9
|
1.0
|
CCP
|
C:A0Z101
|
4.3
|
25.2
|
1.0
|
C
|
A:GLN40
|
4.4
|
17.3
|
1.0
|
CA
|
A:TYR39
|
4.5
|
13.8
|
1.0
|
O
|
A:GLN36
|
4.5
|
18.3
|
1.0
|
CBA
|
C:A0Z101
|
4.7
|
26.8
|
1.0
|
CCR
|
C:A0Z101
|
4.8
|
39.9
|
1.0
|
|
Iodine binding site 8 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 8 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 8 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:I101
b:66.4
occ:1.00
|
IAZ
|
C:A0Z101
|
0.0
|
66.4
|
1.0
|
CCR
|
C:A0Z101
|
2.1
|
39.9
|
1.0
|
O
|
A:HOH780
|
2.8
|
34.3
|
1.0
|
O
|
A:HOH725
|
2.9
|
49.6
|
1.0
|
CCP
|
C:A0Z101
|
3.0
|
25.2
|
1.0
|
CCT
|
C:A0Z101
|
3.2
|
31.9
|
1.0
|
IAX
|
C:A0Z101
|
3.3
|
27.5
|
1.0
|
CBI
|
C:A0Z101
|
3.4
|
34.0
|
1.0
|
CBL
|
C:A0Z101
|
3.5
|
32.4
|
1.0
|
NDB
|
C:A0Z101
|
3.7
|
29.3
|
1.0
|
CCO
|
C:A0Z101
|
4.3
|
22.0
|
1.0
|
CCS
|
C:A0Z101
|
4.4
|
24.5
|
1.0
|
CB
|
A:THR108
|
4.5
|
27.7
|
1.0
|
CG2
|
A:THR108
|
4.6
|
25.8
|
1.0
|
CBF
|
C:A0Z101
|
4.6
|
35.5
|
1.0
|
CG2
|
A:ILE69
|
4.7
|
27.4
|
1.0
|
OG
|
A:SER106
|
4.7
|
30.4
|
1.0
|
CD1
|
A:ILE69
|
4.8
|
28.5
|
1.0
|
CB
|
A:ASP103
|
4.9
|
27.1
|
1.0
|
CCQ
|
C:A0Z101
|
4.9
|
20.6
|
1.0
|
OG1
|
A:THR108
|
4.9
|
31.5
|
1.0
|
|
Iodine binding site 9 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 9 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 9 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:I101
b:33.5
occ:1.00
|
IAW
|
D:A0Z101
|
0.0
|
33.5
|
1.0
|
CCO
|
D:A0Z101
|
2.1
|
25.3
|
1.0
|
CCP
|
D:A0Z101
|
3.1
|
20.8
|
1.0
|
CCQ
|
D:A0Z101
|
3.1
|
20.7
|
1.0
|
IAY
|
D:A0Z101
|
3.5
|
32.0
|
1.0
|
IAX
|
D:A0Z101
|
3.5
|
20.9
|
1.0
|
O
|
A:ILE272
|
4.3
|
29.6
|
1.0
|
CCR
|
D:A0Z101
|
4.4
|
21.6
|
1.0
|
CCS
|
D:A0Z101
|
4.4
|
21.9
|
1.0
|
O
|
A:HOH572
|
4.5
|
30.4
|
1.0
|
CB
|
A:ILE272
|
4.5
|
26.2
|
1.0
|
CCT
|
D:A0Z101
|
4.9
|
21.7
|
1.0
|
|
Iodine binding site 10 out
of 12 in 6spw
Go back to
Iodine Binding Sites List in 6spw
Iodine binding site 10 out
of 12 in the Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140
Mono view
Stereo pair view
|
A full contact list of Iodine with other atoms in the I binding
site number 10 of Structure of Protein Kinase CK2 Catalytic Subunit with the CK2BETA- Competitive Bisubstrate Inhibitor ARC3140 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:I101
b:20.9
occ:1.00
|
IAX
|
D:A0Z101
|
0.0
|
20.9
|
1.0
|
CCP
|
D:A0Z101
|
2.1
|
20.8
|
1.0
|
OD1
|
A:ASP240
|
3.0
|
18.5
|
1.0
|
CCO
|
D:A0Z101
|
3.1
|
25.3
|
1.0
|
CCR
|
D:A0Z101
|
3.1
|
21.6
|
1.0
|
IAW
|
D:A0Z101
|
3.5
|
33.5
|
1.0
|
IAZ
|
D:A0Z101
|
3.5
|
20.8
|
1.0
|
CG
|
A:ASP240
|
3.7
|
17.1
|
1.0
|
CB
|
A:ASP240
|
3.8
|
15.0
|
1.0
|
CA
|
A:ASP240
|
3.9
|
14.9
|
1.0
|
CG2
|
A:VAL243
|
4.2
|
15.3
|
1.0
|
NH2
|
A:ARG244
|
4.2
|
26.2
|
1.0
|
CCQ
|
D:A0Z101
|
4.4
|
20.7
|
1.0
|
CCT
|
D:A0Z101
|
4.4
|
21.7
|
1.0
|
CB
|
A:VAL243
|
4.4
|
14.0
|
1.0
|
CD1
|
A:ILE272
|
4.4
|
33.4
|
1.0
|
N
|
A:ASP240
|
4.5
|
14.9
|
1.0
|
CG1
|
A:VAL243
|
4.6
|
16.1
|
1.0
|
OD2
|
A:ASP240
|
4.7
|
21.1
|
1.0
|
CCS
|
D:A0Z101
|
4.9
|
21.9
|
1.0
|
|
Reference:
K.Niefind,
A.Schnitzler,
A.Uri,
M.Pietsch,
J.Jose,
C.Nienberg,
M.Steinkrueger,
K.Viht.
Unexpected CK2 Beta-Antagonistic Functionality of Bisubstrate Inhibitors Targeting Protein Kinase CK2 Bioorg.Chem. 2020.
ISSN: ISSN 0045-2068
DOI: 10.1016/J.BIOORG.2020.103608
Page generated: Mon Aug 12 00:14:39 2024
|