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Iodine in PDB 6tsg: Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with TetracProtein crystallography data
The structure of Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with Tetrac, PDB code: 6tsg
was solved by
A.Chaikuad,
L.Gellrich,
C.H.Arrowsmith,
A.M.Edwards,
C.Bountra,
D.Merk,
S.Knapp,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iodine Binding Sites:
The binding sites of Iodine atom in the Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with Tetrac
(pdb code 6tsg). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total 4 binding sites of Iodine where determined in the Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with Tetrac, PDB code: 6tsg: Jump to Iodine binding site number: 1; 2; 3; 4; Iodine binding site 1 out of 4 in 6tsgGo back to Iodine Binding Sites List in 6tsg
Iodine binding site 1 out
of 4 in the Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with Tetrac
Mono view Stereo pair view
Iodine binding site 2 out of 4 in 6tsgGo back to Iodine Binding Sites List in 6tsg
Iodine binding site 2 out
of 4 in the Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with Tetrac
Mono view Stereo pair view
Iodine binding site 3 out of 4 in 6tsgGo back to Iodine Binding Sites List in 6tsg
Iodine binding site 3 out
of 4 in the Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with Tetrac
Mono view Stereo pair view
Iodine binding site 4 out of 4 in 6tsgGo back to Iodine Binding Sites List in 6tsg
Iodine binding site 4 out
of 4 in the Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (Pparg) in Complex with Tetrac
Mono view Stereo pair view
Reference:
L.Gellrich,
P.Heitel,
J.Heering,
W.Kilu,
J.Pollinger,
T.Goebel,
A.Kahnt,
S.Arifi,
W.Pogoda,
A.Paulke,
D.Steinhilber,
E.Proschak,
M.Wurglics,
M.Schubert-Zsilavecz,
A.Chaikuad,
S.Knapp,
I.Bischoff,
R.Furst,
D.Merk.
L-Thyroxin and the Nonclassical Thyroid Hormone Tetrac Are Potent Activators of Ppar Gamma. J.Med.Chem. V. 63 6727 2020.
Page generated: Sun Dec 13 19:49:02 2020
ISSN: ISSN 0022-2623 PubMed: 32356658 DOI: 10.1021/ACS.JMEDCHEM.9B02150 |
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