Iodine in PDB 6vrl: Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with I-Paroxetine and 8B6 Fab

The binding sites of Iodine atom in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with I-Paroxetine and 8B6 Fab (pdb code 6vrl). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with I-Paroxetine and 8B6 Fab, PDB code: 6vrl:

Iodine binding site 1 out of 1 in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with I-Paroxetine and 8B6 Fab


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with I-Paroxetine and 8B6 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:I704 b:72.7 occ:1.00 I13 A:RFY704 0.0 72.7 1.0 C10 A:RFY704 2.1 72.7 1.0 C11 A:RFY704 3.0 72.7 1.0 C09 A:RFY704 3.0 72.7 1.0 CB A:THR497 3.6 82.3 1.0 CG1 A:VAL501 3.7 73.3 1.0 CB A:VAL501 3.7 73.3 1.0 CD1 A:ILE172 3.8 77.5 1.0 CG2 A:ILE168 3.8 71.9 1.0 CG2 A:VAL501 4.0 73.3 1.0 CA A:THR497 4.0 82.3 1.0 CE1 A:PHE335 4.0 61.8 1.0 O A:THR497 4.1 82.3 1.0 CG2 A:THR497 4.2 82.3 1.0 C A:THR497 4.3 82.3 1.0 C12 A:RFY704 4.3 72.7 1.0 C08 A:RFY704 4.4 72.7 1.0 CD1 A:PHE335 4.5 61.8 1.0 CG1 A:ILE172 4.6 77.5 1.0 OG1 A:THR497 4.6 82.3 1.0 CE1 A:PHE341 4.7 64.7 1.0 C07 A:RFY704 4.9 72.7 1.0

J.A.Coleman, V.Navratna, D.Antermite, D.Yang, J.Bull, E.Gouaux. Molecular Basis For the Binding of the Antidepressant Paroxetine at the Central Site of the Human Serotonin Transporter To Be Published.