Iodine in PDB 7dsq: Overall Structure of the LAT1-4F2HC Bound with 3,5-Diiodo-L-Tyrosine

The binding sites of Iodine atom in the Overall Structure of the LAT1-4F2HC Bound with 3,5-Diiodo-L-Tyrosine (pdb code 7dsq). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the Overall Structure of the LAT1-4F2HC Bound with 3,5-Diiodo-L-Tyrosine, PDB code: 7dsq:
Jump to Iodine binding site number: 1; 2;

Iodine binding site 1 out of 2 in the Overall Structure of the LAT1-4F2HC Bound with 3,5-Diiodo-L-Tyrosine


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Overall Structure of the LAT1-4F2HC Bound with 3,5-Diiodo-L-Tyrosine within 5.0Å range: probe atom residue distance (Å) B Occ B:I601 b:20.0 occ:1.00 I1 B:TYI601 0.0 20.0 1.0 CE1 B:TYI601 2.1 20.0 1.0 ND2 B:ASN404 2.6 82.1 1.0 O B:HOH704 2.6 77.7 1.0 CD1 B:TYI601 3.0 20.0 1.0 CZ B:TYI601 3.1 20.0 1.0 OH B:TYI601 3.3 20.0 1.0 CZ B:PHE400 3.6 88.0 1.0 CG B:ASN404 3.7 82.1 1.0 CE2 B:PHE400 3.9 88.0 1.0 CE1 B:PHE400 4.1 88.0 1.0 O B:HOH707 4.3 66.6 1.0 N B:GLY256 4.4 56.6 1.0 CG B:TYI601 4.4 20.0 1.0 CE2 B:TYI601 4.4 20.0 1.0 OD1 B:ASN404 4.4 82.1 1.0 CA B:GLY255 4.4 60.5 1.0 CB B:ASN404 4.5 82.1 1.0 CD2 B:PHE400 4.7 88.0 1.0 O B:HOH710 4.7 82.1 1.0 C B:GLY255 4.8 60.5 1.0 O B:HOH706 4.8 59.9 1.0 CD2 B:TYI601 4.9 20.0 1.0 CD1 B:PHE400 4.9 88.0 1.0

Iodine binding site 2 out of 2 in the Overall Structure of the LAT1-4F2HC Bound with 3,5-Diiodo-L-Tyrosine


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Overall Structure of the LAT1-4F2HC Bound with 3,5-Diiodo-L-Tyrosine within 5.0Å range: probe atom residue distance (Å) B Occ B:I601 b:20.0 occ:1.00 I2 B:TYI601 0.0 20.0 1.0 CE2 B:TYI601 2.1 20.0 1.0 CE2 B:TYR259 2.6 53.9 1.0 CG2 B:THR62 2.7 56.2 1.0 CZ B:TYI601 3.0 20.0 1.0 CD2 B:TYI601 3.0 20.0 1.0 CZ B:TYR259 3.1 53.9 1.0 OH B:TYI601 3.2 20.0 1.0 OH B:TYR259 3.3 53.9 1.0 CD2 B:TYR259 3.3 53.9 1.0 CA B:GLY256 4.0 56.6 1.0 CB B:THR62 4.0 56.2 1.0 O B:HOH709 4.1 42.1 1.0 CE1 B:TYR259 4.1 53.9 1.0 O B:THR62 4.2 56.2 1.0 CE1 B:TYI601 4.3 20.0 1.0 CG B:TYR259 4.3 53.9 1.0 CG B:TYI601 4.3 20.0 1.0 O B:GLY256 4.6 56.6 1.0 CD1 B:TYR259 4.7 53.9 1.0 C B:THR62 4.7 56.2 1.0 CA B:THR62 4.8 56.2 1.0 CD1 B:TYI601 4.8 20.0 1.0 C B:GLY256 4.8 56.6 1.0 N B:GLY256 5.0 56.6 1.0

R.H.Yan, Y.N.Li, Y.Y.Zhang, X.Y.Zhong, Q.Zhou. Mechanism of Substrate Transport and Inhibition of the Human Heteromeric LAT1-4F2HC Amino Acid Transporters To Be Published.