Iodine in PDB 7eox: Protease Structure From Euphorbia Resinifera

The structure of Protease Structure From Euphorbia Resinifera, PDB code: 7eox was solved by J.Siritapetawee, J.Attarataya, R.Charoenwattanasatien, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.01 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	67.673, 112.88, 201.801, 90, 90, 90
R / Rfree (%)	20.3 / 23.7

The binding sites of Iodine atom in the Protease Structure From Euphorbia Resinifera (pdb code 7eox). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 4 binding sites of Iodine where determined in the Protease Structure From Euphorbia Resinifera, PDB code: 7eox:
Jump to Iodine binding site number: 1; 2; 3; 4;

Iodine binding site 1 out of 4 in the Protease Structure From Euphorbia Resinifera


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Protease Structure From Euphorbia Resinifera within 5.0Å range: probe atom residue distance (Å) B Occ A:I702 b:25.0 occ:1.00 O A:HOH932 3.6 28.1 1.0 N A:SER380 3.6 23.2 1.0 NH1 A:ARG328 3.6 32.0 1.0 CD A:ARG328 4.0 30.9 1.0 CA A:ALA379 4.0 21.9 1.0 CG1 A:VAL480 4.0 27.2 1.0 CE2 A:PHE381 4.0 23.4 1.0 CE1 A:PHE326 4.1 28.4 1.0 CD2 A:PHE381 4.2 22.4 1.0 CB A:ALA379 4.2 22.9 1.0 C A:ALA379 4.3 21.5 1.0 CB A:ARG328 4.3 29.3 1.0 CB A:SER380 4.4 24.6 1.0 CD1 A:PHE326 4.4 27.2 1.0 CG2 A:VAL480 4.4 26.2 1.0 CG2 A:VAL403 4.4 27.6 1.0 CG A:ARG328 4.5 28.7 1.0 CB A:VAL480 4.5 24.7 1.0 CA A:SER380 4.6 24.2 1.0 CG1 A:VAL403 4.6 28.0 1.0 CZ A:ARG328 4.7 34.8 1.0 NE A:ARG328 4.8 32.2 1.0 N A:PHE381 5.0 25.1 1.0

Iodine binding site 2 out of 4 in the Protease Structure From Euphorbia Resinifera


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Protease Structure From Euphorbia Resinifera within 5.0Å range: probe atom residue distance (Å) B Occ A:I703 b:31.4 occ:1.00 NZ A:LYS214 3.5 25.4 1.0 CA A:GLY180 3.6 30.6 1.0 CE A:LYS214 3.7 26.2 1.0 CE2 B:TYR269 4.0 23.3 1.0 CA B:GLY271 4.1 24.3 1.0 N A:TYR181 4.2 26.9 1.0 CD2 A:TYR181 4.2 22.3 1.0 CD B:ARG277 4.2 34.5 1.0 CE2 A:TYR181 4.3 21.2 1.0 C A:GLY180 4.3 31.4 1.0 CB A:SER211 4.3 25.6 1.0 OG A:SER211 4.4 25.6 1.0 O B:GLY271 4.5 27.6 1.0 OH B:TYR269 4.5 25.6 1.0 C B:GLY271 4.6 25.6 1.0 CB B:ARG277 4.6 26.9 1.0 CZ B:TYR269 4.8 22.6 1.0 CG2 A:THR217 4.8 21.0 1.0 CG A:TYR181 4.9 22.4 1.0 CD2 B:TYR269 4.9 23.0 1.0 N A:GLY180 4.9 28.9 1.0 O A:HOH942 4.9 33.9 1.0 O B:HOH1045 4.9 29.6 1.0 CZ A:TYR181 5.0 20.5 1.0

Iodine binding site 3 out of 4 in the Protease Structure From Euphorbia Resinifera


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 3 of Protease Structure From Euphorbia Resinifera within 5.0Å range: probe atom residue distance (Å) B Occ B:I703 b:20.5 occ:1.00 O B:HOH953 3.5 23.6 1.0 N B:SER380 3.6 18.4 1.0 NH1 B:ARG328 3.7 22.3 1.0 CA B:ALA379 4.0 18.3 1.0 CD B:ARG328 4.0 23.8 1.0 CG1 B:VAL480 4.1 19.9 1.0 CB B:ALA379 4.1 19.4 1.0 CB B:ARG328 4.2 21.4 1.0 CE2 B:PHE381 4.2 16.9 1.0 CE1 B:PHE326 4.2 26.1 1.0 CD2 B:PHE381 4.3 15.1 1.0 CB B:SER380 4.3 21.9 1.0 C B:ALA379 4.3 17.9 1.0 CG2 B:VAL480 4.4 21.2 1.0 CG B:ARG328 4.4 23.0 1.0 CG2 B:VAL403 4.5 17.8 1.0 CB B:VAL480 4.5 20.0 1.0 CD1 B:PHE326 4.5 23.6 1.0 CA B:SER380 4.6 19.9 1.0 CG1 B:VAL403 4.6 21.3 1.0 CZ B:ARG328 4.7 25.3 1.0 NE B:ARG328 4.8 24.3 1.0

Iodine binding site 4 out of 4 in the Protease Structure From Euphorbia Resinifera


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 4 of Protease Structure From Euphorbia Resinifera within 5.0Å range: probe atom residue distance (Å) B Occ B:I704 b:28.2 occ:1.00 NZ B:LYS214 3.5 28.1 1.0 CA B:GLY180 3.7 22.3 1.0 CE B:LYS214 3.7 26.4 1.0 CE2 A:TYR269 4.0 21.6 1.0 CA A:GLY271 4.1 21.7 1.0 O A:HOH1032 4.1 36.7 1.0 N B:TYR181 4.2 22.1 1.0 CD A:ARG277 4.3 30.8 1.0 CD2 B:TYR181 4.3 19.9 1.0 CE2 B:TYR181 4.3 18.5 1.0 OG B:SER211 4.3 22.4 1.0 C B:GLY180 4.4 23.1 1.0 CB B:SER211 4.4 22.1 1.0 O A:GLY271 4.4 23.4 1.0 OH A:TYR269 4.5 24.1 1.0 C A:GLY271 4.6 23.7 1.0 CB A:ARG277 4.6 24.1 1.0 CZ A:TYR269 4.8 23.3 1.0 CG2 B:THR217 4.8 17.8 1.0 CD2 A:TYR269 4.8 22.6 1.0 O B:HOH959 4.9 32.9 1.0 N B:GLY180 4.9 23.9 1.0 CG B:TYR181 4.9 18.0 1.0 CZ B:TYR181 5.0 19.1 1.0

J.Siritapetawee, J.Attarataya, R.Charoenwattanasatien. Sequence Analysis and Crystal Structure of A Glycosylated Protease From Euphorbia Resinifera Latex For Its Proteolytic Activity Aspect. Biotechnol Appl Biochem V. 69 2580 2022.
ISSN: ISSN 1470-8744
PubMed: 34967474
DOI: 10.1002/BAB.2307