Iodine in PDB 7fgk: The Fab Antibody Single Structure Against Tau Protein.

The structure of The Fab Antibody Single Structure Against Tau Protein., PDB code: 7fgk was solved by T.Tsuchida, K.Susa, T.Kibiki, T.Tsuchiya, K.Miyamoto, Y.In, K.Minoura, T.Taniguchi, T.Ishida, K.Tomoo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.82 / 2.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	180.14, 70.78, 41.55, 90, 93.55, 90
R / Rfree (%)	19.9 / 29.9

The binding sites of Iodine atom in the The Fab Antibody Single Structure Against Tau Protein. (pdb code 7fgk). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 2 binding sites of Iodine where determined in the The Fab Antibody Single Structure Against Tau Protein., PDB code: 7fgk:
Jump to Iodine binding site number: 1; 2;

Iodine binding site 1 out of 2 in the The Fab Antibody Single Structure Against Tau Protein.


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of The Fab Antibody Single Structure Against Tau Protein. within 5.0Å range: probe atom residue distance (Å) B Occ H:I301 b:55.5 occ:1.00 O L:HOH456 3.3 36.9 1.0 N H:TRP47 3.6 36.6 1.0 NH1 H:ARG40 3.7 48.4 1.0 O L:HOH458 3.8 49.3 1.0 N L:PHE106 3.9 56.0 1.0 CA H:GLU46 4.1 37.0 1.0 CB H:TRP47 4.2 39.8 1.0 CD2 L:PHE106 4.3 34.2 1.0 ND2 H:ASN61 4.4 55.4 1.0 CA L:VAL105 4.4 61.3 1.0 C H:GLU46 4.4 31.5 1.0 O H:LEU45 4.4 46.7 1.0 CA H:TRP47 4.5 38.3 1.0 O L:TYR104 4.6 57.3 1.0 O L:PHE106 4.6 44.6 1.0 CB L:PHE106 4.7 43.4 1.0 C L:VAL105 4.7 61.3 1.0 CA L:PHE106 4.8 48.0 1.0 CG1 L:VAL105 4.9 65.3 1.0 O H:TRP47 4.9 47.1 1.0 CG H:GLU46 4.9 39.5 1.0 CZ H:ARG40 4.9 48.7 1.0 CB L:VAL105 4.9 66.8 1.0 CG2 L:VAL105 4.9 69.3 1.0 CG L:PHE106 5.0 40.1 1.0 CB H:GLU46 5.0 36.5 1.0

Iodine binding site 2 out of 2 in the The Fab Antibody Single Structure Against Tau Protein.


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of The Fab Antibody Single Structure Against Tau Protein. within 5.0Å range: probe atom residue distance (Å) B Occ L:I301 b:103.2 occ:1.00 O L:HOH442 3.3 72.2 1.0 O L:HOH474 3.5 59.4 1.0 CA L:ALA88 3.7 54.9 1.0 CD L:PRO40 3.9 88.2 1.0 C L:ALA88 3.9 56.8 1.0 N L:ALA88 4.1 58.3 1.0 N L:ILE89 4.2 58.2 1.0 CE L:LYS111 4.2 73.5 1.0 O H:HOH555 4.4 47.5 1.0 CG1 L:ILE89 4.4 68.8 1.0 CD1 L:ILE89 4.5 70.2 1.0 O L:HOH531 4.5 69.3 1.0 O L:ALA88 4.5 49.9 1.0 O L:GLN38 4.5 63.6 1.0 CG L:PRO40 4.6 90.9 1.0 C L:GLU87 4.6 62.7 1.0 NZ L:LYS111 4.6 73.8 1.0 O L:GLU87 4.7 63.0 1.0 CG L:LYS111 4.7 67.2 1.0 N L:PRO40 4.8 84.5 1.0 CB L:ALA88 4.9 54.8 1.0 CA L:GLN39 5.0 82.2 1.0

T.Tsuchida, K.Susa, T.Kibiki, T.Tsuchiya, K.Miyamoto, Y.In, K.Minoura, T.Taniguchi, T.Ishida, K.Tomoo. The Free Structure of the Fab Domain of Antibody That Recognizes the Phf Core Region Vqiink in Tau Protein. To Be Published.