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Iodine in PDB 7jux: Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor TrametinibEnzymatic activity of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Trametinib
All present enzymatic activity of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Trametinib:
2.7.11.1; 2.7.12.2; Protein crystallography data
The structure of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Trametinib, PDB code: 7jux
was solved by
Z.M.Khan,
A.C.Dar,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7jux:
The structure of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Trametinib also contains other interesting chemical elements:
Iodine Binding Sites:
The binding sites of Iodine atom in the Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Trametinib
(pdb code 7jux). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Trametinib, PDB code: 7jux: Iodine binding site 1 out of 1 in 7juxGo back to Iodine Binding Sites List in 7jux
Iodine binding site 1 out
of 1 in the Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Trametinib
Mono view Stereo pair view
Reference:
Z.M.Khan,
A.M.Real,
W.M.Marsiglia,
A.Chow,
M.E.Duffy,
J.R.Yerabolu,
A.P.Scopton,
A.C.Dar.
Structural Basis For the Action of the Drug Trametinib at Ksr-Bound Mek. Nature 2020.
Page generated: Sun Dec 13 20:00:20 2020
ISSN: ESSN 1476-4687 PubMed: 32927473 DOI: 10.1038/S41586-020-2760-4 |
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