Iodine in PDB 7qs2: Crystal Structure of B30.2 Pryspry Domain of TRIM15

The structure of Crystal Structure of B30.2 Pryspry Domain of TRIM15, PDB code: 7qs2 was solved by A.Chaikuad, R.Zhubi, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.23 / 1.70
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	54.764, 54.764, 125.265, 90, 90, 90
R / Rfree (%)	16.9 / 19.9

The binding sites of Iodine atom in the Crystal Structure of B30.2 Pryspry Domain of TRIM15 (pdb code 7qs2). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 4 binding sites of Iodine where determined in the Crystal Structure of B30.2 Pryspry Domain of TRIM15, PDB code: 7qs2:
Jump to Iodine binding site number: 1; 2; 3; 4;

Iodine binding site 1 out of 4 in the Crystal Structure of B30.2 Pryspry Domain of TRIM15


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structure of B30.2 Pryspry Domain of TRIM15 within 5.0Å range: probe atom residue distance (Å) B Occ A:I501 b:15.7 occ:1.00 O A:HOH664 3.6 22.5 1.0 NH2 A:ARG331 3.6 14.2 1.0 O A:PRO300 3.8 13.3 1.0 C A:PRO300 4.1 13.4 1.0 CG A:GLN301 4.1 15.8 1.0 CA A:GLN301 4.2 14.3 1.0 CD A:PRO326 4.2 18.0 1.0 N A:GLN301 4.3 13.9 1.0 CG A:PRO326 4.3 19.0 1.0 CB A:PRO300 4.3 14.0 1.0 CZ A:ARG331 4.5 14.2 1.0 NH1 A:ARG331 4.5 14.1 1.0 CD2 A:LEU325 4.7 20.0 1.0 CB A:GLN301 4.7 14.6 1.0 CA A:PRO300 4.9 13.8 1.0 CG A:PRO300 5.0 14.3 1.0

Iodine binding site 2 out of 4 in the Crystal Structure of B30.2 Pryspry Domain of TRIM15


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Crystal Structure of B30.2 Pryspry Domain of TRIM15 within 5.0Å range: probe atom residue distance (Å) B Occ A:I502 b:29.8 occ:0.80 O1 A:EDO513 2.7 35.2 1.0 C1 A:EDO513 3.4 31.8 1.0 C A:SER328 3.7 16.4 1.0 N A:PRO329 3.8 16.5 1.0 O A:SER328 4.0 14.9 1.0 CA A:PRO329 4.1 17.8 1.0 CD A:PRO329 4.2 19.1 1.0 N A:SER328 4.3 18.3 1.0 NZ A:LYS375 4.4 16.1 1.0 CA A:SER328 4.4 17.3 1.0 CE A:LYS375 4.4 16.4 1.0 C2 A:EDO513 4.6 33.5 1.0 CB A:PRO329 4.7 19.8 1.0 CB A:ASP327 4.8 21.1 1.0 O2 A:EDO513 4.8 24.4 1.0 C A:ASP327 4.9 19.3 1.0 O A:HOH632 5.0 19.8 1.0

Iodine binding site 3 out of 4 in the Crystal Structure of B30.2 Pryspry Domain of TRIM15


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 3 of Crystal Structure of B30.2 Pryspry Domain of TRIM15 within 5.0Å range: probe atom residue distance (Å) B Occ A:I503 b:31.3 occ:0.50 O A:HOH689 2.8 38.2 1.0 N A:LYS457 3.5 17.6 1.0 NZ A:LYS456 3.6 43.8 1.0 CA A:LYS456 3.9 19.2 1.0 CB A:LYS457 4.0 23.8 1.0 CD A:LYS456 4.0 31.0 1.0 CE A:LYS456 4.1 37.5 1.0 CD A:ARG320 4.1 50.8 1.0 CE2 A:TYR318 4.2 20.5 1.0 C A:LYS456 4.3 17.0 1.0 CG A:ARG320 4.3 44.3 1.0 CA A:LYS457 4.4 19.3 1.0 CB A:LYS456 4.4 21.4 1.0 CB A:ARG320 4.5 35.3 1.0 O A:HOH643 4.7 19.9 1.0 CD2 A:TYR318 4.8 18.6 1.0 CG A:LYS456 4.8 25.6 1.0 NH1 A:ARG320 4.8 70.8 1.0 NE A:ARG320 4.8 60.6 1.0 OH A:TYR318 5.0 22.7 1.0 CZ A:TYR318 5.0 19.4 1.0

Iodine binding site 4 out of 4 in the Crystal Structure of B30.2 Pryspry Domain of TRIM15


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 4 of Crystal Structure of B30.2 Pryspry Domain of TRIM15 within 5.0Å range: probe atom residue distance (Å) B Occ A:I504 b:46.8 occ:0.50 NE2 A:GLN356 2.9 36.4 1.0 OG1 A:THR462 3.3 22.6 1.0 O A:ASP354 3.6 18.0 1.0 CD A:GLN356 3.8 32.3 1.0 CG A:GLN356 3.8 25.4 1.0 CB A:THR462 3.9 22.6 1.0 C A:ASP354 3.9 18.8 1.0 N A:THR462 3.9 17.8 1.0 SG A:CYS460 4.0 20.1 0.5 O A:CYS460 4.0 18.0 1.0 N A:LEU355 4.2 17.1 1.0 C A:LEU461 4.2 18.1 1.0 N A:GLN356 4.2 16.2 1.0 CA A:LEU355 4.2 17.7 1.0 C A:LEU355 4.2 17.4 1.0 C A:CYS460 4.3 17.3 1.0 SG A:CYS460 4.3 25.1 0.5 CB A:ASP354 4.3 22.9 1.0 CA A:LEU461 4.4 16.6 1.0 CB A:CYS460 4.4 20.1 0.5 N A:LEU461 4.5 15.5 1.0 CA A:THR462 4.6 19.4 1.0 CB A:GLN356 4.6 21.2 1.0 O A:HOH674 4.7 32.9 1.0 O A:LEU355 4.8 17.9 1.0 CA A:ASP354 4.8 20.7 1.0 O A:LEU461 4.9 18.3 1.0 OE1 A:GLN356 4.9 42.2 1.0 CB A:CYS460 4.9 19.0 0.5

A.Chaikuad, R.Zhubi, S.Knapp, Structural Genomics Consortium (Sgc). Crystal Structure of B30.2 Pryspry Domain of TRIM15 To Be Published.