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Iodine in PDB 8bw9: Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp

Enzymatic activity of Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp

All present enzymatic activity of Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp:
2.7.12.2;

Other elements in 8bw9:

The structure of Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Fluorine (F) 1 atom

Iodine Binding Sites:

The binding sites of Iodine atom in the Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp (pdb code 8bw9). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp, PDB code: 8bw9:

Iodine binding site 1 out of 1 in 8bw9

Go back to Iodine Binding Sites List in 8bw9
Iodine binding site 1 out of 1 in the Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Cryo-Em Structure of the Raf Activating Complex Ksr-Mek-Cnk-Hyp within 5.0Å range:
probe atom residue distance (Å) B Occ
C:I402

b:190.8
occ:1.00
I17 C:QOM402 0.0 190.8 1.0
C14 C:QOM402 2.1 146.3 1.0
C13 C:QOM402 3.0 141.9 1.0
C15 C:QOM402 3.0 145.4 1.0
CG2 C:VAL146 3.7 90.4 1.0
N C:ASP227 4.1 104.6 1.0
SD C:MET162 4.1 126.2 1.0
CB C:CYS226 4.2 88.5 1.0
C12 C:QOM402 4.3 145.3 1.0
C16 C:QOM402 4.3 138.7 1.0
CA C:CYS226 4.4 80.8 1.0
CE2 C:PHE228 4.5 99.7 1.0
CD1 C:LEU137 4.6 148.0 1.0
OD1 C:ASP227 4.7 114.5 1.0
CB C:MET162 4.7 135.6 1.0
CD2 C:LEU137 4.7 143.5 1.0
C C:CYS226 4.8 90.7 1.0
CG C:LEU137 4.8 146.3 1.0
C11 C:QOM402 4.9 141.9 1.0
O C:VAL146 4.9 102.0 1.0
CA C:ASP227 5.0 106.5 1.0
CZ C:PHE228 5.0 100.7 1.0

Reference:

P.Maisonneuve, S.Malha, F.Bergeron-Labrecque, M.Lefrancois, X.I.Ma, G.Arseneault, R.Fronzes, I.Kurinov, F.Sicheri, M.Therrien. The Cnk-Hyp Scaffolding Complex Promotes Raf Activation By Enhancing Ksr-Mek Interaction To Be Published 2024.
DOI: 10.1038/S41594-024-01233-6
Page generated: Mon Aug 12 02:31:07 2024

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