Iodine in PDB 8ct8: Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex

All present enzymatic activity of Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex:
3.1.3.48;

The structure of Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex, PDB code: 8ct8 was solved by R.Fakih, R.H.Goldstein, G.Kozlov, K.Gehring, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.44 / 2.50
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	83.311, 83.311, 238.188, 90, 90, 90
R / Rfree (%)	22.5 / 27.5

The binding sites of Iodine atom in the Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex (pdb code 8ct8). This binding sites where shown within 5.0 Angstroms radius around Iodine atom.
In total 3 binding sites of Iodine where determined in the Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex, PDB code: 8ct8:
Jump to Iodine binding site number: 1; 2; 3;

Iodine binding site 1 out of 3 in the Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 1 of Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:I601 b:40.8 occ:1.00 N B:LYS428 3.7 42.1 1.0 N A:LYS428 3.7 39.5 1.0 N B:ILE427 3.8 49.7 1.0 N A:ILE427 3.8 45.4 1.0 CB A:SER409 3.8 57.6 1.0 CB B:ILE427 3.9 45.6 1.0 O A:SER409 4.0 45.9 1.0 CB A:ILE427 4.0 57.8 1.0 O B:SER409 4.1 54.2 1.0 CB B:TYR426 4.2 43.3 1.0 CB B:LYS428 4.2 43.6 1.0 CB A:TYR426 4.2 51.8 1.0 CA B:ILE427 4.2 45.2 1.0 CB A:LYS428 4.2 41.6 1.0 CA A:ILE427 4.3 47.8 1.0 CD1 B:TYR426 4.3 50.6 1.0 CB B:SER409 4.4 47.6 1.0 OG A:SER409 4.4 42.4 1.0 CD1 A:TYR426 4.4 46.6 1.0 C B:ILE427 4.4 43.9 1.0 C A:ILE427 4.5 39.1 1.0 CA B:LYS428 4.5 46.4 1.0 CA A:LYS428 4.6 41.3 1.0 CA A:SER409 4.6 51.6 1.0 C B:TYR426 4.6 45.5 1.0 C A:TYR426 4.6 40.0 1.0 C A:SER409 4.7 47.4 1.0 CG1 B:ILE427 4.7 48.3 1.0 CG B:TYR426 4.7 42.1 1.0 CG1 A:ILE427 4.7 46.6 1.0 CA A:TYR426 4.7 45.3 1.0 CA B:TYR426 4.8 52.4 1.0 C B:SER409 4.8 47.6 1.0 CG A:TYR426 4.8 39.5 1.0 CA B:SER409 4.8 43.6 1.0 CG2 B:ILE427 4.9 59.4 1.0

Iodine binding site 2 out of 3 in the Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 2 of Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:I201 b:49.2 occ:1.00 N C:GLY144 3.4 53.1 1.0 CD C:ARG139 4.0 35.3 1.0 CA C:GLY144 4.0 47.6 1.0 CG C:ARG143 4.0 57.7 1.0 CB C:ARG139 4.3 44.7 1.0 CG C:ARG139 4.3 48.1 1.0 O C:HOH310 4.4 34.5 1.0 C C:ARG143 4.4 43.8 1.0 CA C:ARG143 4.5 42.2 1.0 NE C:ARG139 4.7 56.2 1.0 CB C:ARG143 4.9 37.0 1.0

Iodine binding site 3 out of 3 in the Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex


Mono view


Stereo pair view

A full contact list of Iodine with other atoms in the I binding site number 3 of Crystal Structure of Drosophila Melanogaster Prl/Cbs-Pair Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:I201 b:52.7 occ:1.00 N D:GLY144 3.5 56.5 1.0 CD D:ARG139 4.0 46.6 1.0 CA D:GLY144 4.2 53.4 1.0 CB D:ARG139 4.3 49.5 1.0 CG D:ARG139 4.4 45.3 1.0 CA D:ARG143 4.4 57.0 1.0 C D:ARG143 4.4 53.5 1.0 NE D:ARG139 4.7 59.4 1.0 CB D:ARG143 4.8 56.8 1.0

R.Fakih, R.H.Goldstein, G.Kozlov, K.Gehring. From Flies to Fungi: A Structural and Biochemical Study of Phosphatases of Regenerating Liver (Prl) To Be Published.