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Atomistry » Iodine » PDB 3cjq-3fnl » 3eqb | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iodine » PDB 3cjq-3fnl » 3eqb » |
Iodine in PDB 3eqb: X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and MgatpEnzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
All present enzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp:
2.7.12.2; Protein crystallography data
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp, PDB code: 3eqb
was solved by
J.F.Ohren,
A.Pavlovsky,
E.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3eqb:
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp also contains other interesting chemical elements:
Iodine Binding Sites:
The binding sites of Iodine atom in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
(pdb code 3eqb). This binding sites where shown within
5.0 Angstroms radius around Iodine atom.
In total only one binding site of Iodine was determined in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp, PDB code: 3eqb: Iodine binding site 1 out of 1 in 3eqbGo back to![]() ![]()
Iodine binding site 1 out
of 1 in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
![]() Mono view ![]() Stereo pair view
Reference:
J.S.Warmus,
C.Flamme,
L.Y.Zhang,
S.Barrett,
A.Bridges,
H.Chen,
R.Gowan,
M.Kaufman,
J.Sebolt-Leopold,
W.Leopold,
R.Merriman,
J.Ohren,
A.Pavlovsky,
S.Przybranowski,
H.Tecle,
H.Valik,
C.Whitehead,
E.Zhang.
2-Alkylamino- and Alkoxy-Substituted 2-Amino-1,3,4-Oxadiazoles-O-Alkyl Benzohydroxamate Esters Replacements Retain the Desired Inhibition and Selectivity Against Mek (Map Erk Kinase). Bioorg.Med.Chem.Lett. V. 18 6171 2008.
Page generated: Sun Aug 11 15:06:14 2024
ISSN: ISSN 0960-894X PubMed: 18951019 DOI: 10.1016/J.BMCL.2008.10.015 |
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